Neonatal modulation of serum cytokine profiles by a specific mixture of anti-inflammatory neutral and acidic oligosaccharides in preterm infants

Jolice Van Den Berg, Ninke van Zwieteren, Elisabeth A.M. Westerbeek, Johan Garssen, Ruurd M. van Elburg

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Infections are common in preterm infants and cause differences in cytokine levels. Aim of this study was to measure cytokine levels in preterm infants during the first year of life and to determine the effect of feeding a specific non-digestible carbohydrate mixture (scGOS/lcFOS/pAOS). Furthermore, other perinatal factors in relation to these cytokine levels were analysed.In a randomized controlled trial, preterm infants (GA
Original languageEnglish
Pages (from-to)188-195
Number of pages8
JournalCytokine
Volume64
Issue number1
DOIs
Publication statusPublished - 1 Oct 2013

Keywords

  • Cytokine profiles
  • Neutral and acidic oligosaccharides
  • One year follow up
  • Preterm infants
  • ISRCTN16211826
  • antibiotic agent
  • corticosteroid
  • cytokine
  • fructose oligosaccharide
  • galactose oligosaccharide
  • gamma interferon
  • interleukin 10
  • interleukin 17
  • interleukin 1beta
  • interleukin 2
  • interleukin 4
  • interleukin 6
  • interleukin 8
  • maltodextrin
  • oligosaccharide
  • pectin derived acidic oligosaccharide
  • placebo
  • tumor necrosis factor alpha
  • unclassified drug
  • adult
  • antiinflammatory activity
  • article
  • birth weight
  • controlled study
  • enteric feeding
  • female
  • gestational age
  • human
  • infant
  • major clinical study
  • male
  • newborn
  • prematurity
  • priority journal
  • protein blood level
  • randomized controlled trial

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