N-glycosylation and glycoengineering in the mushroom-forming fungus Schizophyllum commune

E. Berends

Research output: ThesisDoctoral thesis 1 (Research UU / Graduation UU)


The market for N-glycosylated therapeutic proteins represents multi-billion dollars in sales and is growing more than 10% each year. As a consequence there is a need for cost-effective production platforms that display correct and homogeneous N-glycosylation. In this thesis, we investigate the use of mushroom forming basidiomycetes for the production of N-glycosylated therapeutic proteins
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Utrecht University
  • Bosch, H.J., Primary supervisor
  • Wösten, Han, Supervisor
  • Lugones, Luis, Co-supervisor
Award date21 Jan 2013
Print ISBNs978-90-393-5960-0
Publication statusPublished - 21 Jan 2013


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