Monolithic and Small Particle Column Materials for Application in Proteomics

    Research output: ThesisDoctoral thesis 1 (Research UU / Graduation UU)

    Abstract

    In this thesis the influence of the capillary liquid chromatography separation on the identification of protein digests is studied. In the first part the chromatographic parameters for silica monolithic columns are optimized to obtain a high throughput or a high separation performance. in the second part different column materials, monolithic and ultra-small particulate columns, are compared. In the last part trends and suggestions for future research are given.
    Original languageEnglish
    QualificationDoctor of Philosophy
    Awarding Institution
    • Utrecht University
    Supervisors/Advisors
    • Heck, Albert, Primary supervisor
    Award date19 Dec 2012
    Publisher
    Print ISBNs978-90-393-5867-2
    Publication statusPublished - 19 Dec 2012

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