Modulation of phagocytic cell function

P. A.J. Henricks*, J. Verhoef, F. P. Nijkamp

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Phagocytosis is an important factor in the defense of the host against all kinds of microorganisms. The process of phagocytosis of microorganisms by phagocytes can be separated into distinct but interrelated phases: adherence, chemotaxis, opsonization, attachment, ingestion, degranulation and killing. Phagocytosis is accompanied by an increase in oxygen metabolism in which H2O2 and activated oxygen species are generated. Modulation of phagocytic cell function can be brought about by a variety of substances. Microorganisms produce and contain components which influence the process of phagocytosis. Surrounding tissue cells and the phagocytes themselves produce biologically active molecules that modulate phagocytosis.

Original languageEnglish
Pages (from-to)165-188
Number of pages24
JournalVeterinary Research Communications
Volume10
Issue number1
DOIs
Publication statusPublished - Dec 1986

Bibliographical note

Copyright:
Copyright 2007 Elsevier B.V., All rights reserved.

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