Method for identifying natural drug analogues

P.C. Burgers; J.J.A. van Kampen; P.J.A. Ruttink; T.M. Luider

Method for identifying natural drug analogues

P.C. Burgers (Inventor)
, J.J.A. van Kampen (Inventor)
, P.J.A. Ruttink (Inventor)
, T.M. Luider (Inventor)

Dept of Chemistry

extern

Research output: Patent › Other research output

Abstract

The invention relates to the use of a MALDI mass spectrometer for the detection of natural analogues of small-molecule drugs in biological samples, wherein said MALDI mass spectrometer comprises a matrix comprising a matrix material comprising a porphyrin ring capable of holding an alkali metal ion in an out-of-plane position relative to the plane of the porphyrin ring, and wherein said matrix material has a molecular weight at least higher than that of a small-molecule drug.

Original language	Undefined/Unknown
Patent number	WO/2008/048087
Publication status	Published - 24 Apr 2008

Access to Document

http://www.wipo.int/pctdb/en/wo.jsp?IA=NL2006000530&WO=2008048087&DISPLAY=STATUS

Cite this

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title = "Method for identifying natural drug analogues",

abstract = "The invention relates to the use of a MALDI mass spectrometer for the detection of natural analogues of small-molecule drugs in biological samples, wherein said MALDI mass spectrometer comprises a matrix comprising a matrix material comprising a porphyrin ring capable of holding an alkali metal ion in an out-of-plane position relative to the plane of the porphyrin ring, and wherein said matrix material has a molecular weight at least higher than that of a small-molecule drug.",

author = "P.C. Burgers and \{van Kampen\}, J.J.A. and P.J.A. Ruttink and T.M. Luider",

year = "2008",

month = apr,

day = "24",

language = "Undefined/Unknown",

type = "Patent",

note = "WO/2008/048087",

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TY - PAT

T1 - Method for identifying natural drug analogues

AU - Burgers, P.C.

AU - van Kampen, J.J.A.

AU - Ruttink, P.J.A.

AU - Luider, T.M.

PY - 2008/4/24

Y1 - 2008/4/24

N2 - The invention relates to the use of a MALDI mass spectrometer for the detection of natural analogues of small-molecule drugs in biological samples, wherein said MALDI mass spectrometer comprises a matrix comprising a matrix material comprising a porphyrin ring capable of holding an alkali metal ion in an out-of-plane position relative to the plane of the porphyrin ring, and wherein said matrix material has a molecular weight at least higher than that of a small-molecule drug.

AB - The invention relates to the use of a MALDI mass spectrometer for the detection of natural analogues of small-molecule drugs in biological samples, wherein said MALDI mass spectrometer comprises a matrix comprising a matrix material comprising a porphyrin ring capable of holding an alkali metal ion in an out-of-plane position relative to the plane of the porphyrin ring, and wherein said matrix material has a molecular weight at least higher than that of a small-molecule drug.

M3 - Patent

M1 - WO/2008/048087

ER -