Mechanistic studies of the oxidative addition of aryl halides to ni(0) centers bearing phosphine ligands

Pablo Marcelo Pérez-García; Marc Etienne Moret

doi:10.2533/CHIMIA.2020.495

Mechanistic studies of the oxidative addition of aryl halides to ni(0) centers bearing phosphine ligands

Pablo Marcelo Pérez-García
, Marc Etienne Moret^*

^*Corresponding author for this work

Sub Organic Chemistry and Catalysis

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The oxidative addition of aryl halides is a common entry point in catalytic cycles for cross-coupling and related reactions. In the case of phosphine-supported nickel(0) fragments, the formation of reactive Ni(ii)-aryl products often competes with the production of Ni(i) species. Here, recent advances in the mechanistic understanding of these reactions are highlighted. In particular, the denticity of the supporting ligand has a significant influence on the outcome of the reaction.

Original language	English
Pages (from-to)	495-498
Number of pages	4
Journal	Chimia
Volume	74
Issue number	6
DOIs	https://doi.org/10.2533/CHIMIA.2020.495
Publication status	Published - 6 Jun 2020

Funding

This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 715060).

Keywords

Cross-coupling
Nickel
Oxidative addition
Phosphine ligands
Reaction mechanisms

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abstract = "The oxidative addition of aryl halides is a common entry point in catalytic cycles for cross-coupling and related reactions. In the case of phosphine-supported nickel(0) fragments, the formation of reactive Ni(ii)-aryl products often competes with the production of Ni(i) species. Here, recent advances in the mechanistic understanding of these reactions are highlighted. In particular, the denticity of the supporting ligand has a significant influence on the outcome of the reaction.",

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N2 - The oxidative addition of aryl halides is a common entry point in catalytic cycles for cross-coupling and related reactions. In the case of phosphine-supported nickel(0) fragments, the formation of reactive Ni(ii)-aryl products often competes with the production of Ni(i) species. Here, recent advances in the mechanistic understanding of these reactions are highlighted. In particular, the denticity of the supporting ligand has a significant influence on the outcome of the reaction.

AB - The oxidative addition of aryl halides is a common entry point in catalytic cycles for cross-coupling and related reactions. In the case of phosphine-supported nickel(0) fragments, the formation of reactive Ni(ii)-aryl products often competes with the production of Ni(i) species. Here, recent advances in the mechanistic understanding of these reactions are highlighted. In particular, the denticity of the supporting ligand has a significant influence on the outcome of the reaction.

KW - Cross-coupling

KW - Nickel

KW - Oxidative addition

KW - Phosphine ligands

KW - Reaction mechanisms

UR - https://www.scopus.com/pages/publications/85086754460

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DO - 10.2533/CHIMIA.2020.495

M3 - Article

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EP - 498

JO - Chimia

JF - Chimia

IS - 6

ER -

Mechanistic studies of the oxidative addition of aryl halides to ni(0) centers bearing phosphine ligands

Abstract

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Keywords

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