Maintenance of tolerance to cow's milk in atopic individuals is characterized by high levels of specific immunoglobulin G4

B. Ruiter, E.F. Knol, R.J.J. Van Neerven, J. Garssen, C.A.F.M. Bruijnzeel-Koomen, A.C. Knulst, E. Van Hoffen

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Background: The central role of specific IgE in cow's milk allergy (CMA) is well documented. However, less is known about the function of other immunoglobulin isotypes in allergy and tolerance to cow's milk proteins (CMPs). Objective: To determine differences in the antibody responses that are associated with allergy and tolerance to cow's milk in allergic, atopic and non-atopic individuals of different age groups. Methods: Nineteen infants (
Original languageEnglish
Pages (from-to)1103-1110
Number of pages8
JournalClinical and Experimental Allergy
Volume37
Issue number7
DOIs
Publication statusPublished - 1 Jul 2007

Keywords

  • Farmacie/Biofarmaceutische wetenschappen (FARM)
  • Farmacie(FARM)
  • Biomedische technologie en medicijnen
  • Immunology
  • Pharmacology
  • Overig medisch onderzoek

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