Machine learning-based assessment of the built environment on prevalence and severity risks of acne

H Yang*, X Cui , H Wang, M Helbich, C Yin, X Chen, J Wen, C Ren, L Xiang, A Xu, Q Ju, T Zhu, J Chen, S Tian, M Dijst, L He

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Understanding the determinants of acne prevalence and severity is crucial for effective prevention and management of this dermatological condition. While urban interventions have long-lasting, far-reaching, and costly implications for health promotion, the associations between built environments (BEs) and acne need further investigation. To address this gap, our study utilizes a nationwide cross-sectional sample of 23,488 undergraduates from 90 campuses in China to conduct a comprehensive analysis. We examined the combined and specific contributions of BEs in relation to other domains of acne-related factors in acne development. By employing the optimal random forest model, our findings reveal that BEs collectively ranked as the second-largest contributors to both the overall prevalence of acne among all participants and the severity of acne in the affected individuals. Moreover, our analysis identifies curvilinear associations between acne and most BEs, underscoring the importance of incorporating BE considerations into the prevention, diagnosis, and management of acne.
Original languageEnglish
Article number100235
Number of pages13
JournalCell Reports Sustainability
Volume1
Issue number10
DOIs
Publication statusPublished - 25 Oct 2024

Bibliographical note

Publisher Copyright:
© 2024 The Author(s)

Funding

This project received support from the Program for Innovative Research Team from the Ministry of Education of China (grant no. IRT17-R49), the National Key Research and Development Program of China (grant no. 2023YFC2509000), and National Natural Science Foundation of China Joint Fund Project (grant no. U22A20310), which contributed to the study design of epidemiological survey and the collection of individual information, including biological and medical attributes, demographic and socioeconomic characteristics, lifestyle factors, and the specific locations of the surveyed campuses. The Key Program of National Natural Science Foundation of China (no. 42330510) and the National Natural Science Foundation of China (no. 42101184) provided support for the study design and collection of neighborhood information encompassing built environments and natural environments. We extend our sincere gratitude to the over 100 dermatologists who participated in the acne diagnosis process and the collection of individuals\u2019 information.

FundersFunder number
National Key Research and Development Program of China2023YFC2509000
Ministry of Education of the People's Republic of ChinaIRT17-R49
National Natural Science Foundation of China42330510, 42101184
National Natural Science Foundation of China Joint Fund ProjectU22A20310

    Keywords

    • acne vulgaris
    • built environment
    • college student
    • machine learning
    • prevalence risk
    • severity

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