Luminescent labeling of nanoparticles: SiO2@LaPO4

Jacobine van Hest*, Andries Meijerink

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review


Nanomaterials are embedded in a variety of products we use daily, e.g. silica nanocrystals are applied in rubber and food. However, more research has to be performed on nano-enabled products to learn more about their environmental and health risks. The demand for guidelines for nanomaterials asks for modelnanosystems that can be traced during their life cycle. In this project, luminescent LaPO4 core particles with sizes ranging from 4 to 8 nm [1] were incorporated into silica nanocrystals. The luminescence properties of the nanocrystal were varied by changing or combining the nature of the lanthanide dopants in the LaPO4 nanocrystal in order to obtain a variety of unique luminescent labels. Silica was grown around the luminescent LaPO4 cores using the reverse micelle method (see Fig. 39.1a) [2]. Silica spheres with sizes between 35 and 85 nm could be obtained by changing the polarity of the dispersion medium of the LaPO4 nanocrystals. The nanocrystals preserved their luminescence properties after silica coating (see Fig. 39.1b). The fluorescent nanoparticles make it possible to use combined fluorescence and electron microscopy for the analysis of the nanoparticles down to the single particle level – and is in progress.

Original languageEnglish
Title of host publicationNATO Science for Peace and Security Series B: Physics and Biophysics
Number of pages2
Publication statusPublished - 2017

Publication series

NameNATO Science for Peace and Security Series B: Physics and Biophysics
ISSN (Print)18746500


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