Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection

Jelena Maric-Biresev, Julia P Hunn, Oleg Krut, J Bernd Helms, Sascha Martens, Jonathan C Howard

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    Keyphrases

    Immunology and Microbiology

    Biochemistry, Genetics and Molecular Biology

    Neuroscience