Local bacillus Calmette-Guérin therapy for bovine vulval papilloma and carcinoma

F. W.G. Hill; V. P.M.G. Rutten; M. H. Hoyer; W. R. Klein; J. W. Koten; P. A. Steerenberg; E. J. Ruitenberg; W. Den Otter

doi:10.1007/BF01517180

Local bacillus Calmette-Guérin therapy for bovine vulval papilloma and carcinoma

F. W.G. Hill, V. P.M.G. Rutten^*, M. H. Hoyer, W. R. Klein, J. W. Koten, P. A. Steerenberg, E. J. Ruitenberg, W. Den Otter

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Thirty cows from a pedigree Friesian dairy herd with bovine vulva papilloma and carcinoma were treated by intralesional injections of live bacillus Calmette-Guérin (BCG). This treatment induced total regression of all of six carcinomas. Whilst, after treatment, limited regression was also observed in advanced papillomas, BCG has little or no effect on the early stages of papillomas. This is the first study of BCG therapy in this type of cancer.

Original language	English
Pages (from-to)	49-52
Number of pages	4
Journal	Cancer Immunology Immunotherapy
Volume	39
Issue number	1
DOIs	https://doi.org/10.1007/BF01517180
Publication status	Published - 1 Jan 1994

Keywords

BCG
Bovine vulval papilloma-carcinoma
Immunotherapy

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10.1007/BF01517180

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title = "Local bacillus Calmette-Gu{\'e}rin therapy for bovine vulval papilloma and carcinoma",

abstract = "Thirty cows from a pedigree Friesian dairy herd with bovine vulva papilloma and carcinoma were treated by intralesional injections of live bacillus Calmette-Gu{\'e}rin (BCG). This treatment induced total regression of all of six carcinomas. Whilst, after treatment, limited regression was also observed in advanced papillomas, BCG has little or no effect on the early stages of papillomas. This is the first study of BCG therapy in this type of cancer.",

keywords = "BCG, Bovine vulval papilloma-carcinoma, Immunotherapy",

author = "Hill, {F. W.G.} and Rutten, {V. P.M.G.} and Hoyer, {M. H.} and Klein, {W. R.} and Koten, {J. W.} and Steerenberg, {P. A.} and Ruitenberg, {E. J.} and Otter, {W. Den}",

year = "1994",

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doi = "10.1007/BF01517180",

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AU - Hill, F. W.G.

AU - Rutten, V. P.M.G.

AU - Hoyer, M. H.

AU - Klein, W. R.

AU - Koten, J. W.

AU - Steerenberg, P. A.

AU - Ruitenberg, E. J.

AU - Otter, W. Den

PY - 1994/1/1

Y1 - 1994/1/1

N2 - Thirty cows from a pedigree Friesian dairy herd with bovine vulva papilloma and carcinoma were treated by intralesional injections of live bacillus Calmette-Guérin (BCG). This treatment induced total regression of all of six carcinomas. Whilst, after treatment, limited regression was also observed in advanced papillomas, BCG has little or no effect on the early stages of papillomas. This is the first study of BCG therapy in this type of cancer.

AB - Thirty cows from a pedigree Friesian dairy herd with bovine vulva papilloma and carcinoma were treated by intralesional injections of live bacillus Calmette-Guérin (BCG). This treatment induced total regression of all of six carcinomas. Whilst, after treatment, limited regression was also observed in advanced papillomas, BCG has little or no effect on the early stages of papillomas. This is the first study of BCG therapy in this type of cancer.

KW - BCG

KW - Bovine vulval papilloma-carcinoma

KW - Immunotherapy

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JO - Cancer Immunology Immunotherapy

JF - Cancer Immunology Immunotherapy

IS - 1

ER -

Local bacillus Calmette-Guérin therapy for bovine vulval papilloma and carcinoma

Abstract

Keywords

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