Liquid chromatography-tandem mass spectrometric assay for the PARP inhibitor rucaparib in plasma

Keyphrases

• Mass Spectrometry 100%
• Spectrometric Assay 100%
• PARP Inhibitor (PARPi) 100%
• Rucaparib 100%
• Liquid Chromatography-tandem Mass 100%
• Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS) 50%
• Drug Pharmacokinetics 50%
• Acetonitrile 50%
• Between-day 50%
• Protein Precipitation 50%
• Triple Quadrupole Mass Spectrometer 50%
• Reversed Phase 50%
• Limit of Quantification 50%
• Monitoring Mode 50%
• Eluate 50%
• Plasma Samples 50%
• Chromatographic System 50%
• Gefitinib 50%
• Linear Regression 50%
• Electrospray Interface 50%
• Wild Mice 50%
• Bioanalytics 50%
• Selected Reaction Monitoring 50%
• Analytical Condition 50%

Chemistry

• Rucaparib 100%
• Liquid Chromatography 100%
• Poly(ADPribose) 50%
• Electrosprays 50%
• Pharmacokinetics 50%
• Quadrupole 50%
• Tandem Mass Spectrometry 50%
• Protein Precipitation 50%
• Acetonitrile 50%
• Gefitinib 50%
• Liquid Chromatography Mass Spectrometry 50%

Food Science

• Liquid Chromatography Mass Spectrometry 100%
• Tandem Mass Spectrometry 100%