Ligand-free copper(I) catalyzed N- and O-arylation of aryl halides

E. Sperotto; J.G. de Vries; G.P.M. van Klink; G. van Koten

Ligand-free copper(I) catalyzed N- and O-arylation of aryl halides

E. Sperotto, J.G. de Vries, G.P.M. van Klink, G. van Koten

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Research output: Contribution to journal › Article › Academic › peer-review

Abstract

A simple and industrially viable protocol for C–N and C–O coupling is reported here. Arylation of phenol, benzylamine and imidazole with aryl bromides is achieved using ligand-free Cu(I) halide salts in low catalytic amount (2.5 mol %).

Original language	Undefined/Unknown
Pages (from-to)	7366-7370
Number of pages	5
Journal	Tetrahedron Letters
Volume	48
Issue number	41
Publication status	Published - 2007

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Cite this

@article{565645a3e2634e0aa1b9c605a813c5b4,

title = "Ligand-free copper(I) catalyzed N- and O-arylation of aryl halides",

abstract = "A simple and industrially viable protocol for C–N and C–O coupling is reported here. Arylation of phenol, benzylamine and imidazole with aryl bromides is achieved using ligand-free Cu(I) halide salts in low catalytic amount (2.5 mol %).",

author = "E. Sperotto and {de Vries}, J.G. and {van Klink}, G.P.M. and {van Koten}, G.",

year = "2007",

language = "Undefined/Unknown",

volume = "48",

pages = "7366--7370",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier",

number = "41",

}

TY - JOUR

T1 - Ligand-free copper(I) catalyzed N- and O-arylation of aryl halides

AU - Sperotto, E.

AU - de Vries, J.G.

AU - van Klink, G.P.M.

AU - van Koten, G.

PY - 2007

Y1 - 2007

N2 - A simple and industrially viable protocol for C–N and C–O coupling is reported here. Arylation of phenol, benzylamine and imidazole with aryl bromides is achieved using ligand-free Cu(I) halide salts in low catalytic amount (2.5 mol %).

AB - A simple and industrially viable protocol for C–N and C–O coupling is reported here. Arylation of phenol, benzylamine and imidazole with aryl bromides is achieved using ligand-free Cu(I) halide salts in low catalytic amount (2.5 mol %).

M3 - Article

SN - 0040-4039

VL - 48

SP - 7366

EP - 7370

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 41

ER -