Lifecycle HTA: promising applications and a framework for implementation. An HTAi Global Policy Forum Task Force report

Franz B. Pichler; Meindert Boysen; Nicole Mittmann; Ramiro Gilardino; Andrew Bruce; Kenneth Bond; Rick A. Vreman; Nathalie Largeron; Judit Banhazi; Daniel A. Ollendorf; Mohit Jain; Sheela Upadhyaya; Wim G. Goettsch

doi:10.1017/S0266462324000187

Lifecycle HTA: promising applications and a framework for implementation. An HTAi Global Policy Forum Task Force report

Franz B. Pichler
, Meindert Boysen
, Nicole Mittmann
, Ramiro Gilardino
, Andrew Bruce
, Kenneth Bond
, Rick A. Vreman
, Nathalie Largeron
, Judit Banhazi
, Daniel A. Ollendorf
, Mohit Jain
, Sheela Upadhyaya
, Wim G. Goettsch

Pharmacoepi & Clinical Pharmacology

Research output: Contribution to journal › Review article › peer-review

Abstract

The 2022 Health Technology Assessment International (HTAi) Global Policy Forum (GPF) established the goal of developing a position statement and framework for lifecycle HTA (LC-HTA), through a Task Force leveraging multi-stakeholder monthly discussions and GPF member input. The Task Force developed a working definition: LC-HTA is a systematic process utilizing sequential HTA activities to inform decision making where the evidence base, the health technology itself, or the context in which it is applied, has a potential to meaningfully change at different points in its LC. Four key scenarios were identified where it was considered that an LC-HTA approach would add sufficient value to HTA bodies and their key stakeholders to justify the additional resource burden. Based on the four scenarios, a high-level LC-HTA framework was developed consisting of (i) defining the decision problem, (ii) sequencing of HTA activities, and (iii) developing optimization criteria. Subsequently, the Task Force developed operationalization guidance for LC-HTA in a companion paper

Original language	English
Article number	e50
Number of pages	6
Journal	International Journal of Technology Assessment in Health Care
Volume	40
Issue number	1
Early online date	10 May 2024
DOIs	https://doi.org/10.1017/S0266462324000187 https://doi.org/10.1017/S0266462324000187
Publication status	Published - 10 May 2024

Bibliographical note

Publisher Copyright:
© The Author(s), 2024.

Funding

The development of the two papers by the Lifecycle-HTA Taskforce was made possible with support from the HTAi Global Policy Forum and Ali Powers of the HTAi Global Policy Forum Secretariat who provided administrative and logistical support for the meetings. The Task Force's progress was discussed at two meetings of the HTAi Global Policy Forum. During these meetings, members of the HTAi community provided valuable feedback and direction to guide the development of the manuscripts. The manuscripts were also reviewed by the members of the Science Development and Capacity Building Committee and invited representatives from HTAi's general membership. Specifically, we would like to thank Yingyao Chen, Lesley Dunfield, Karen Facey, Brendan Kearney, Wija Oortwijn, Rebecca Trowman, and Joice Valentin for providing written comments on draft versions of this manuscript.

Funders
Health Technology Assessment international
Capacity Building Committee

Keywords

HTA policy
HTA reassessment
Health technology assessment
Life cycle HTA
Technology lifecycle
Uncertainty

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1017/S0266462324000187

lifecycle-hta-promising-applications-and-a-framework-for-implementation-an-htai-global-policy-forum-task-force-reportFinal published version, 274 KBLicence: CC BY

Cite this

Pichler, F. B., Boysen, M., Mittmann, N., Gilardino, R., Bruce, A., Bond, K., Vreman, R. A., Largeron, N., Banhazi, J., Ollendorf, D. A., Jain, M., Upadhyaya, S., & Goettsch, W. G. (2024). Lifecycle HTA: promising applications and a framework for implementation. An HTAi Global Policy Forum Task Force report. International Journal of Technology Assessment in Health Care, 40(1), Article e50. https://doi.org/10.1017/S0266462324000187, https://doi.org/10.1017/S0266462324000187

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abstract = "The 2022 Health Technology Assessment International (HTAi) Global Policy Forum (GPF) established the goal of developing a position statement and framework for lifecycle HTA (LC-HTA), through a Task Force leveraging multi-stakeholder monthly discussions and GPF member input. The Task Force developed a working definition: LC-HTA is a systematic process utilizing sequential HTA activities to inform decision making where the evidence base, the health technology itself, or the context in which it is applied, has a potential to meaningfully change at different points in its LC. Four key scenarios were identified where it was considered that an LC-HTA approach would add sufficient value to HTA bodies and their key stakeholders to justify the additional resource burden. Based on the four scenarios, a high-level LC-HTA framework was developed consisting of (i) defining the decision problem, (ii) sequencing of HTA activities, and (iii) developing optimization criteria. Subsequently, the Task Force developed operationalization guidance for LC-HTA in a companion paper",

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year = "2024",

month = may,

day = "10",

doi = "10.1017/S0266462324000187",

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Pichler, FB, Boysen, M, Mittmann, N, Gilardino, R, Bruce, A, Bond, K, Vreman, RA, Largeron, N, Banhazi, J, Ollendorf, DA, Jain, M, Upadhyaya, S & Goettsch, WG 2024, 'Lifecycle HTA: promising applications and a framework for implementation. An HTAi Global Policy Forum Task Force report', International Journal of Technology Assessment in Health Care, vol. 40, no. 1, e50. https://doi.org/10.1017/S0266462324000187, https://doi.org/10.1017/S0266462324000187

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AU - Pichler, Franz B.

AU - Boysen, Meindert

AU - Mittmann, Nicole

AU - Gilardino, Ramiro

AU - Bruce, Andrew

AU - Bond, Kenneth

AU - Vreman, Rick A.

AU - Largeron, Nathalie

AU - Banhazi, Judit

AU - Ollendorf, Daniel A.

AU - Jain, Mohit

AU - Upadhyaya, Sheela

AU - Goettsch, Wim G.

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AB - The 2022 Health Technology Assessment International (HTAi) Global Policy Forum (GPF) established the goal of developing a position statement and framework for lifecycle HTA (LC-HTA), through a Task Force leveraging multi-stakeholder monthly discussions and GPF member input. The Task Force developed a working definition: LC-HTA is a systematic process utilizing sequential HTA activities to inform decision making where the evidence base, the health technology itself, or the context in which it is applied, has a potential to meaningfully change at different points in its LC. Four key scenarios were identified where it was considered that an LC-HTA approach would add sufficient value to HTA bodies and their key stakeholders to justify the additional resource burden. Based on the four scenarios, a high-level LC-HTA framework was developed consisting of (i) defining the decision problem, (ii) sequencing of HTA activities, and (iii) developing optimization criteria. Subsequently, the Task Force developed operationalization guidance for LC-HTA in a companion paper

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KW - HTA reassessment

KW - Health technology assessment

KW - Life cycle HTA

KW - Technology lifecycle

KW - Uncertainty

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DO - 10.1017/S0266462324000187

M3 - Review article

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SN - 0266-4623

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JO - International Journal of Technology Assessment in Health Care

JF - International Journal of Technology Assessment in Health Care

IS - 1

M1 - e50

ER -

Lifecycle HTA: promising applications and a framework for implementation. An HTAi Global Policy Forum Task Force report

Abstract

Bibliographical note

Funding

Keywords

UN SDGs

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