Legal substance use and the development of a DSM-IV cannabis use disorder during adolescence: the TRAILS study

  • Andrea Prince van Leeuwen
  • , Hanneke E. Creemers
  • , Frank C. Verhulst
  • , Wilma A. M. Vollebergh
  • , Johan Ormel
  • , Floor van Oort
  • , Anja C. Huizink*
  • *Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

AimsTo examine whether early onset of tobacco or alcohol use, and continued use of tobacco or alcohol in early adolescence, are related to a higher likelihood of developing a cannabis use disorder during adolescence.

Design and settingData were used from four consecutive assessment waves of the TRacking Adolescents' Individual Lives Survey (TRAILS), a general Dutch population study. TRAILS is an ongoing longitudinal study that will follow the same group of adolescents from the ages of 10 to 24 years.

ParticipantsThe sample consisted of 1108 (58% female) adolescents (mean ages at the four assessment waves are 11.09, 13.56, 16.27 and 19.05 years, respectively)

MeasurementsCannabis use disorders were assessed using the Composite International Diagnostic Interview 3.0 (CIDI). Adolescent tobacco and alcohol use were assessed using self-report questionnaires.

FindingsEarly-onset tobacco use [odds ratio (OR)=1.82, confidence interval (CI)=1.05-3.14, P0.05), was associated with a higher likelihood of developing a cannabis use disorder. Similarly, adolescents who reported continued use of tobacco (OR=2.47, CI=1.02-5.98, P0.05), were more likely to develop a cannabis use disorder.

ConclusionsEarly-onset and continued tobacco use appear to predict the development of a cannabis use disorder in adolescence, whereas early onset and continued alcohol use do not.

Original languageEnglish
Pages (from-to)303-311
Number of pages9
JournalAddiction
Volume109
Issue number2
DOIs
Publication statusPublished - Feb 2014

Funding

This research is part of the TRacking Adolescents' Individual Lives Survey (TRAILS). Participating centres of TRAILS include various departments of the University Medical Center and University of Groningen, the Erasmus University Medical Center Rotterdam, the University of Utrecht, the Radboud Medical Center Nijmegen and the Parnassia Bavo group, all in the Netherlands. TRAILS has been supported financially by various grants from the Netherlands Organization for Scientific Research NWO (Medical Research Council programme grant GB-MW 940-38-011; ZonMW Brainpower grant 100-001-004; ZonMw Risk Behavior and Dependence grants 60-60600-97-118; ZonMw Culture and Health grant 261-98-710; Social Sciences Council medium-sized investment grants GB-MaGW 480-01-006 and GB-MaGW 480-07-001; Social Sciences Council project grants GB-MaGW 452-04-314 and GB-MaGW 452-06-004; NWO large-sized investment grant 175.010.2003.005; NWO Longitudinal Survey and Panel Funding 481-08-013), the Dutch Ministry of Justice (WODC), the European Science Foundation (EuroSTRESS project FP-006), Biobanking and Biomolecular Resources Research Infrastructure BBMRI-NL (CP 32) and the participating universities. We are grateful to all adolescents, their parents and teachers who participated in this research and to everyone who worked on this project and made it possible. The present analysis was supported by the Netherlands Organization for Scientific Research (NWO)Vidi Scheme, the Netherlands (452-06-004 to A.C.H. and A.P.v.L.).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Adolescence
  • alcohol use
  • cannabis use
  • DSM-IV cannabis use disorder
  • tobacco use
  • DUTCH ADOLESCENTS
  • DRUG-USE
  • EARLY ADULTHOOD
  • RISK
  • DEPENDENCE
  • ALCOHOL
  • TRAJECTORIES
  • ABUSE
  • PREADOLESCENTS
  • INVOLVEMENT

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