Jaw-muscle activity changes after the induction of osteoarthrosis in the temporomandibular joint by mechanical loading

Nobuhiko Kawai*, Eiji Tanaka, Geerling E. J. Langenbach, Tim van Wessel, Ryota Sano, Theo M. G. J. van Eijden, Kazuo Tanne

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Aims: To examine the effect of mechanical loading on the induction of temporomandibular joint osteoarthrosis (TMJ OA). Methods: Mechanical stress was applied to the rat TMJ by forced jaw opening of 3 hours a day for 5 days. The electromyographic (EMG) activity of the masseter and digastric muscles was continuously monitored by radio-telemetry. It was characterized by the total time each muscle was active (duty time), the number of bursts, and the average burst length. For histologic analysis, rats were sacrificed before, immediately after, and 3 weeks after the period of forced jaw opening. Results: The condylar cartilage revealed OA-like lesions with a decrease in the number of chondrocytes immediately after forced jaw opening. Three weeks later, the OA-like lesions were repaired to some extent. After the forced jaw opening, the duty time of the masseter increased, whereas the duty time of the digastric decreased significantly (P

Original languageEnglish
Pages (from-to)153-162
Number of pages10
JournalJournal of Orofacial Pain
Volume22
Issue number2
Publication statusPublished - 2008

Keywords

  • electromyography
  • jaw muscle
  • mechanical stress
  • osteoarthrosis
  • temporomandibular joint
  • PAIN
  • RABBIT
  • RAT
  • MODEL
  • RESORPTION
  • DISORDERS
  • RECEPTORS
  • MOVEMENT
  • ADJUVANT
  • LENGTHS

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