Is placebo analgesia mediated by endogenous opioids?: A systematic review

G ter Riet; A J de Craen; A de Boer; A G Kessels

Is placebo analgesia mediated by endogenous opioids? A systematic review

G ter Riet, A J de Craen, A de Boer, A G Kessels

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

This systematic review assesses six experimental studies into the mechanism of placebo analgesia in human subjects suffering from clinical pain or experimentally induced ischaemic arm pain. Due to their sophisticated designs, these studies probably provide the best evidence that placebo analgesia exists. They also indicate that placebo analgesia is mediated by endogenous opiates. However, there seems to be room for additional studies.

Original language	English
Pages (from-to)	273-275
Number of pages	3
Journal	Pain
Volume	76
Issue number	3
Publication status	Published - Jun 1998

Keywords

Analgesia
Animals
Endorphins
Humans
Placebo Effect

Cite this

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title = "Is placebo analgesia mediated by endogenous opioids?: A systematic review",

abstract = "This systematic review assesses six experimental studies into the mechanism of placebo analgesia in human subjects suffering from clinical pain or experimentally induced ischaemic arm pain. Due to their sophisticated designs, these studies probably provide the best evidence that placebo analgesia exists. They also indicate that placebo analgesia is mediated by endogenous opiates. However, there seems to be room for additional studies.",

keywords = "Analgesia, Animals, Endorphins, Humans, Placebo Effect",

author = "{ter Riet}, G and {de Craen}, {A J} and {de Boer}, A and Kessels, {A G}",

year = "1998",

month = jun,

language = "English",

volume = "76",

pages = "273--275",

journal = "Pain",

issn = "0304-3959",

publisher = "Lippincott Williams and Wilkins",

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TY - JOUR

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T2 - A systematic review

AU - ter Riet, G

AU - de Craen, A J

AU - de Boer, A

AU - Kessels, A G

PY - 1998/6

Y1 - 1998/6

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AB - This systematic review assesses six experimental studies into the mechanism of placebo analgesia in human subjects suffering from clinical pain or experimentally induced ischaemic arm pain. Due to their sophisticated designs, these studies probably provide the best evidence that placebo analgesia exists. They also indicate that placebo analgesia is mediated by endogenous opiates. However, there seems to be room for additional studies.

KW - Analgesia

KW - Animals

KW - Endorphins

KW - Humans

KW - Placebo Effect

M3 - Article

C2 - 9718245

SN - 0304-3959

VL - 76

SP - 273

EP - 275

JO - Pain

JF - Pain

IS - 3

ER -

Is placebo analgesia mediated by endogenous opioids? A systematic review

Abstract

Keywords

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