Influence of early feeding patterns on eczema development in high-risk infants

M. Tang, A. Rijnierse, A. Nauta, R. Boyle, J. Hourihane, W. Chiang, M. Chua, P. Smith, M. Gold, J. Ziegler, J. Peake, P. Quinn, R. Rao, N. Brown, J. Garssen, J. Warner

Research output: Contribution to conferenceAbstractAcademic


Introduction: This study examined the relationship between timing of introduction of complementary feeding, type of early milk feeding (breast milk, standard cow's milk formula [CMF], prebiotic-supplemented hydrolysed cow's milk formula [pHF-OS]) and development of eczema in infants at increased risk of allergy. Objectives: This is a sub-study of the PATCH randomized-controlled trial which evaluated the effect of pHF-OS on prevention of eczema [ISRCTN65195597]. PATCH participants were randomized to receive pHF-OS or CMF for 6 months. A breastfed reference group was included. Cumulative incidence of eczema was assessed at age 18 months and 5 years. Age at introduction of complementary feeding was categorized as early-introduction (
Original languageEnglish
Number of pages1
Publication statusPublished - 1 Aug 2017
EventEuropean Academy of Allergy and Clinical Immunology Congress - Helsinki, Finland
Duration: 17 Jun 201721 Jun 2017


ConferenceEuropean Academy of Allergy and Clinical Immunology Congress


  • prebiotic agent
  • allergy
  • animal model
  • artificial milk
  • breast feeding
  • breast milk
  • child
  • complementary feeding
  • controlled study
  • disease course
  • eczema
  • ethnicity
  • family history
  • feeding behavior
  • female
  • high risk infant
  • human
  • hydrolysis
  • incidence
  • infant
  • male
  • milk
  • preschool child
  • prevention
  • proportional hazards model
  • randomized controlled trial


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