Abstract
In the present study it was investigated, at different time points, whether or not an endotoxin-evoked influx of inflammatory cells in the respiratory airways of the guinea pig is accompanied by bronchial hyperresponsiveness in vivo and/or in vitro. Experimental induced airway inflammation by endotoxin does not induce bronchial hyperresponsiveness. Therefore it is important to determine whether non-allergic bronchial hyperreactivity is correlated with a change in cellular function and/or synthesis of specific mediators.
| Original language | English |
|---|---|
| Pages (from-to) | 94-96 |
| Number of pages | 3 |
| Journal | Agents and Actions |
| Volume | 23 |
| Issue number | 1-2 |
| Publication status | Published - 28 Mar 1988 |
Keywords
- endotoxin
- animal experiment
- asthma
- guinea pig
- inflammation
- male
- nonhuman