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In vivo veritas: Electron cryotomography of cells

  • Jürgen M. Plitzko*
  • , Achilleas S. Frangakis
  • , Stephan Nickell
  • , Friedrich Förster
  • , Ariane Gross
  • , Wolfgang Baumeister
  • *Corresponding author for this work
  • Molecular Structural Biology
  • Max Planck Institute of Biochemistry

Research output: Contribution to journalArticleAcademic

Abstract

Automated electron cryotomography enables the study of organelles or whole cells embedded in vitrified ice in a close-to-life state and with a resolution of a few nanometers. This technology will provide new vistas of the supramolecular architecture inside cells that orchestrates higher cellular functions.

Original languageEnglish
JournalTrends in Biotechnology
Volume20
Issue number8
DOIs
Publication statusPublished - 1 Aug 2002
Externally publishedYes

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