In vivo veritas: Electron cryotomography of cells

Jürgen M. Plitzko*, Achilleas S. Frangakis, Stephan Nickell, Friedrich Förster, Ariane Gross, Wolfgang Baumeister

*Corresponding author for this work

Research output: Contribution to journalArticleAcademic

Abstract

Automated electron cryotomography enables the study of organelles or whole cells embedded in vitrified ice in a close-to-life state and with a resolution of a few nanometers. This technology will provide new vistas of the supramolecular architecture inside cells that orchestrates higher cellular functions.

Original languageEnglish
JournalTrends in Biotechnology
Volume20
Issue number8
DOIs
Publication statusPublished - 1 Aug 2002
Externally publishedYes

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