In-Hospital Production of Medicines: Preparing for Disruption

Shona Kalkman; Marlous Arentshorst; Jarno Hoekman; Wouter Boon; Esther Uijtendaal; Ghislaine van Thiel; Ellen Moors

doi:10.1016/j.tibtech.2019.09.011

In-Hospital Production of Medicines: Preparing for Disruption

Shona Kalkman
, Marlous Arentshorst
, Jarno Hoekman
, Wouter Boon
, Esther Uijtendaal
, Ghislaine van Thiel
, Ellen Moors

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

In-hospital production of affordable medicines holds potential to address problems of drug accessibility. However, expanding the scope of magistral preparation to include high-cost drugs and complex biologicals gives rise to new challenges. We discuss ethical and regulatory complexities faced by Dutch initiatives defying the current pharmaceutical system through magistral preparation.

Original language	English
Pages (from-to)	1045-1047
Journal	Trends in Biotechnology
Volume	38
Issue number	10
DOIs	https://doi.org/10.1016/j.tibtech.2019.09.011
Publication status	Published - 2020

Keywords

in-hospital production
magistral preparation
disruptive innovation
ethics
regulatory science

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10.1016/j.tibtech.2019.09.011

1-s2.0-S0167779919302434-mainFinal published version, 363 KB

http://www.sciencedirect.com/science/article/pii/S0167779919302434

Cite this

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title = "In-Hospital Production of Medicines: Preparing for Disruption",

abstract = "In-hospital production of affordable medicines holds potential to address problems of drug accessibility. However, expanding the scope of magistral preparation to include high-cost drugs and complex biologicals gives rise to new challenges. We discuss ethical and regulatory complexities faced by Dutch initiatives defying the current pharmaceutical system through magistral preparation.",

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AU - Kalkman, Shona

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AU - Hoekman, Jarno

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AU - Uijtendaal, Esther

AU - van Thiel, Ghislaine

AU - Moors, Ellen

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KW - in-hospital production

KW - magistral preparation

KW - disruptive innovation

KW - ethics

KW - regulatory science

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JO - Trends in Biotechnology

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In-Hospital Production of Medicines: Preparing for Disruption

Abstract

Keywords

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