Impaired specific immunoreactivity in cows with hepatic lipidosis

G. H. Wentink; V. P.M.G. Rutten; T. S.G.A.M. Van Den Ingh; A. Hoek; K. E. Müller; Th Wensing

doi:10.1016/S0165-2427(96)05743-1

Impaired specific immunoreactivity in cows with hepatic lipidosis

G. H. Wentink^*, V. P.M.G. Rutten, T. S.G.A.M. Van Den Ingh, A. Hoek, K. E. Müller, Th Wensing

^*Corresponding author for this work

Immunology

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

In this study, hepatic lipidosis in cows was experimentally induced by offering an energy surplus during the dry period. Liver triacylglycerol (TAG) was 16% in the experimental group. In the control group fed the same diet in restricted quantities, liver TAG was about 7%. The animals of both groups were vaccinated with tetanus vaccine at Day 3 after parturition. It was demonstrated that the cows with high liver TAG percentages had lower humoral and cellular (P < 0.05) immunological responses compared with the animals with low liver TAG levels at Day 14 after vaccination. The results obtained in the high TAG group support the notion that the frequent occurrence of aspecific infections in cows with hepatic lipidosis may be due to impaired immunoreactivity.

Original language	English
Pages (from-to)	77-83
Number of pages	7
Journal	Veterinary Immunology and Immunopathology
Volume	56
Issue number	1-2
DOIs	https://doi.org/10.1016/S0165-2427(96)05743-1
Publication status	Published - May 1997

Keywords

Hepatic lipidosis
Immune response

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0165-2427(96)05743-1

Cite this

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title = "Impaired specific immunoreactivity in cows with hepatic lipidosis",

abstract = "In this study, hepatic lipidosis in cows was experimentally induced by offering an energy surplus during the dry period. Liver triacylglycerol (TAG) was 16% in the experimental group. In the control group fed the same diet in restricted quantities, liver TAG was about 7%. The animals of both groups were vaccinated with tetanus vaccine at Day 3 after parturition. It was demonstrated that the cows with high liver TAG percentages had lower humoral and cellular (P < 0.05) immunological responses compared with the animals with low liver TAG levels at Day 14 after vaccination. The results obtained in the high TAG group support the notion that the frequent occurrence of aspecific infections in cows with hepatic lipidosis may be due to impaired immunoreactivity.",

keywords = "Hepatic lipidosis, Immune response",

author = "Wentink, {G. H.} and Rutten, {V. P.M.G.} and {Van Den Ingh}, {T. S.G.A.M.} and A. Hoek and M{\"u}ller, {K. E.} and Th Wensing",

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language = "English",

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T1 - Impaired specific immunoreactivity in cows with hepatic lipidosis

AU - Wentink, G. H.

AU - Rutten, V. P.M.G.

AU - Van Den Ingh, T. S.G.A.M.

AU - Hoek, A.

AU - Müller, K. E.

AU - Wensing, Th

PY - 1997/5

Y1 - 1997/5

N2 - In this study, hepatic lipidosis in cows was experimentally induced by offering an energy surplus during the dry period. Liver triacylglycerol (TAG) was 16% in the experimental group. In the control group fed the same diet in restricted quantities, liver TAG was about 7%. The animals of both groups were vaccinated with tetanus vaccine at Day 3 after parturition. It was demonstrated that the cows with high liver TAG percentages had lower humoral and cellular (P < 0.05) immunological responses compared with the animals with low liver TAG levels at Day 14 after vaccination. The results obtained in the high TAG group support the notion that the frequent occurrence of aspecific infections in cows with hepatic lipidosis may be due to impaired immunoreactivity.

AB - In this study, hepatic lipidosis in cows was experimentally induced by offering an energy surplus during the dry period. Liver triacylglycerol (TAG) was 16% in the experimental group. In the control group fed the same diet in restricted quantities, liver TAG was about 7%. The animals of both groups were vaccinated with tetanus vaccine at Day 3 after parturition. It was demonstrated that the cows with high liver TAG percentages had lower humoral and cellular (P < 0.05) immunological responses compared with the animals with low liver TAG levels at Day 14 after vaccination. The results obtained in the high TAG group support the notion that the frequent occurrence of aspecific infections in cows with hepatic lipidosis may be due to impaired immunoreactivity.

KW - Hepatic lipidosis

KW - Immune response

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VL - 56

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JO - Veterinary Immunology and Immunopathology

JF - Veterinary Immunology and Immunopathology

IS - 1-2

ER -

Impaired specific immunoreactivity in cows with hepatic lipidosis

Abstract

Keywords

UN SDGs

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