Immunity to Campylobacter: its role in risk assessment and epidemiology

Arie H Havelaar; Wilfrid van Pelt; C Wim Ang; Jaap A Wagenaar; Jos P M van Putten; Uwe Gross; Diane G Newell

doi:10.1080/10408410802636017

Immunity to Campylobacter: its role in risk assessment and epidemiology

Arie H Havelaar
, Wilfrid van Pelt
, C Wim Ang
, Jaap A Wagenaar
, Jos P M van Putten
, Uwe Gross
, Diane G Newell

Research output: Contribution to journal › Review article › peer-review

Abstract

Acquired immunity is an important factor in the epidemiology of campylobacteriosis in the developing world, apparently limiting symptomatic infection to children of less than two years. However, also in developed countries the highest incidence is observed in children under five years and the majority of Campylobacter infections are asymptomatic, which may be related to the effects of immunity and/or the ingested doses. Not accounting for immunity in epidemiological studies may lead to biased results due to the misclassification of Campylobacter-exposed but apparently healthy persons as unexposed. In risk assessment studies, health risks may be overestimated when immunity is neglected.

Original language	English
Pages (from-to)	1-22
Number of pages	22
Journal	Critical Reviews in Microbiology
Volume	35
Issue number	1
DOIs	https://doi.org/10.1080/10408410802636017
Publication status	Published - 2009

Keywords

Age Factors
Biomedical Research/methods
Campylobacter/immunology
Campylobacter Infections/epidemiology
Developing Countries
Epidemiologic Research Design
Humans
Incidence
Infant
Infant, Newborn
Risk Assessment

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/10408410802636017

Havelaar-Crit Rev Microbiol 2009 35 1-22Final published version, 738 KBLicence: Taverne

Cite this

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title = "Immunity to Campylobacter: its role in risk assessment and epidemiology",

abstract = "Acquired immunity is an important factor in the epidemiology of campylobacteriosis in the developing world, apparently limiting symptomatic infection to children of less than two years. However, also in developed countries the highest incidence is observed in children under five years and the majority of Campylobacter infections are asymptomatic, which may be related to the effects of immunity and/or the ingested doses. Not accounting for immunity in epidemiological studies may lead to biased results due to the misclassification of Campylobacter-exposed but apparently healthy persons as unexposed. In risk assessment studies, health risks may be overestimated when immunity is neglected.",

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T2 - its role in risk assessment and epidemiology

AU - Havelaar, Arie H

AU - van Pelt, Wilfrid

AU - Ang, C Wim

AU - Wagenaar, Jaap A

AU - van Putten, Jos P M

AU - Gross, Uwe

AU - Newell, Diane G

PY - 2009

Y1 - 2009

N2 - Acquired immunity is an important factor in the epidemiology of campylobacteriosis in the developing world, apparently limiting symptomatic infection to children of less than two years. However, also in developed countries the highest incidence is observed in children under five years and the majority of Campylobacter infections are asymptomatic, which may be related to the effects of immunity and/or the ingested doses. Not accounting for immunity in epidemiological studies may lead to biased results due to the misclassification of Campylobacter-exposed but apparently healthy persons as unexposed. In risk assessment studies, health risks may be overestimated when immunity is neglected.

AB - Acquired immunity is an important factor in the epidemiology of campylobacteriosis in the developing world, apparently limiting symptomatic infection to children of less than two years. However, also in developed countries the highest incidence is observed in children under five years and the majority of Campylobacter infections are asymptomatic, which may be related to the effects of immunity and/or the ingested doses. Not accounting for immunity in epidemiological studies may lead to biased results due to the misclassification of Campylobacter-exposed but apparently healthy persons as unexposed. In risk assessment studies, health risks may be overestimated when immunity is neglected.

KW - Age Factors

KW - Biomedical Research/methods

KW - Campylobacter/immunology

KW - Campylobacter Infections/epidemiology

KW - Developing Countries

KW - Epidemiologic Research Design

KW - Humans

KW - Incidence

KW - Infant

KW - Infant, Newborn

KW - Risk Assessment

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DO - 10.1080/10408410802636017

M3 - Review article

C2 - 19514906

SN - 1040-841X

VL - 35

SP - 1

EP - 22

JO - Critical Reviews in Microbiology

JF - Critical Reviews in Microbiology

IS - 1

ER -

Immunity to Campylobacter: its role in risk assessment and epidemiology

Abstract

Keywords

UN SDGs

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