Human milk fatty acid composition of allergic and non-allergic mothers: The ulm spatz health study

Linda P. Siziba; Leonie Lorenz; Bernd Stahl; Marko Mank; Tamas Marosvölgyi; Tamas Decsi; Dietrich Rothenbacher; Jon Genuneit

doi:10.3390/nu12061740

Human milk fatty acid composition of allergic and non-allergic mothers: The ulm spatz health study

Linda P. Siziba^*
, Leonie Lorenz
, Bernd Stahl
, Marko Mank
, Tamas Marosvölgyi
, Tamas Decsi
, Dietrich Rothenbacher
, Jon Genuneit

^*Corresponding author for this work

Leipzig University
Ulm University
University of Pecs

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The aim of this study was to determine the differences in human milk fatty acid composition in relation to maternal allergy within a large birth cohort study using statistical methods accounting for the correlations that exist in compositional data. We observed marginal differences in human milk fatty acid composition of allergic and non-allergic mothers. However, our results do not support the hypothesis that human milk fatty acid composition is influenced by allergy or that it differs between mothers with or without allergy. Observed differences in our results between transformed and untransformed fatty acid data call for re-evaluation of previous, as well as future, studies using statistical methods appropriate for compositionality of fatty acid data.

Original language	English
Article number	1740
Number of pages	8
Journal	Nutrients
Volume	12
Issue number	6
DOIs	https://doi.org/10.3390/nu12061740
Publication status	Published - Jun 2020

Funding

Funding: This research was funded by Danone Nutricia Research.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Fatty acids
Human milk
Maternal allergy

Access to Document

10.3390/nu12061740

nutrients-12-01740-v2Final published version, 250 KB

Cite this

@article{02d1187ca5b645ed80f1313b2c0222fa,

title = "Human milk fatty acid composition of allergic and non-allergic mothers: The ulm spatz health study",

abstract = "The aim of this study was to determine the differences in human milk fatty acid composition in relation to maternal allergy within a large birth cohort study using statistical methods accounting for the correlations that exist in compositional data. We observed marginal differences in human milk fatty acid composition of allergic and non-allergic mothers. However, our results do not support the hypothesis that human milk fatty acid composition is influenced by allergy or that it differs between mothers with or without allergy. Observed differences in our results between transformed and untransformed fatty acid data call for re-evaluation of previous, as well as future, studies using statistical methods appropriate for compositionality of fatty acid data.",

keywords = "Fatty acids, Human milk, Maternal allergy",

author = "Siziba, \{Linda P.\} and Leonie Lorenz and Bernd Stahl and Marko Mank and Tamas Marosv{\"o}lgyi and Tamas Decsi and Dietrich Rothenbacher and Jon Genuneit",

year = "2020",

month = jun,

doi = "10.3390/nu12061740",

language = "English",

volume = "12",

journal = "Nutrients",

issn = "2072-6643",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "6",

}

TY - JOUR

T1 - Human milk fatty acid composition of allergic and non-allergic mothers

T2 - The ulm spatz health study

AU - Siziba, Linda P.

AU - Lorenz, Leonie

AU - Stahl, Bernd

AU - Mank, Marko

AU - Marosvölgyi, Tamas

AU - Decsi, Tamas

AU - Rothenbacher, Dietrich

AU - Genuneit, Jon

PY - 2020/6

Y1 - 2020/6

N2 - The aim of this study was to determine the differences in human milk fatty acid composition in relation to maternal allergy within a large birth cohort study using statistical methods accounting for the correlations that exist in compositional data. We observed marginal differences in human milk fatty acid composition of allergic and non-allergic mothers. However, our results do not support the hypothesis that human milk fatty acid composition is influenced by allergy or that it differs between mothers with or without allergy. Observed differences in our results between transformed and untransformed fatty acid data call for re-evaluation of previous, as well as future, studies using statistical methods appropriate for compositionality of fatty acid data.

AB - The aim of this study was to determine the differences in human milk fatty acid composition in relation to maternal allergy within a large birth cohort study using statistical methods accounting for the correlations that exist in compositional data. We observed marginal differences in human milk fatty acid composition of allergic and non-allergic mothers. However, our results do not support the hypothesis that human milk fatty acid composition is influenced by allergy or that it differs between mothers with or without allergy. Observed differences in our results between transformed and untransformed fatty acid data call for re-evaluation of previous, as well as future, studies using statistical methods appropriate for compositionality of fatty acid data.

KW - Fatty acids

KW - Human milk

KW - Maternal allergy

UR - https://www.scopus.com/pages/publications/85086325452

U2 - 10.3390/nu12061740

DO - 10.3390/nu12061740

M3 - Article

C2 - 32532066

AN - SCOPUS:85086325452

SN - 2072-6643

VL - 12

JO - Nutrients

JF - Nutrients

IS - 6

M1 - 1740

ER -

Human milk fatty acid composition of allergic and non-allergic mothers: The ulm spatz health study

Abstract

Funding

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this