TY - JOUR
T1 - Human exposure to aerosol from indoor gas stove cooking and the resulting nervous system responses
AU - Amouei Torkmahalleh, Mehdi
AU - Naseri, Motahareh
AU - Nurzhan, Sholpan
AU - Gabdrashova, Raikhangul
AU - Bekezhankyzy, Zhibek
AU - Gimnkhan, Aidana
AU - Malekipirbazari, Milad
AU - Jouzizadeh, Mojtaba
AU - Tabesh, Mahsa
AU - Farrokhi, Hamta
AU - Mehri-Dehnavi, Hossein
AU - Khanbabaie, Reza
AU - Sadeghi, Sahar
AU - Khatir, Ali Alizadeh
AU - Sabanov, Sergei
AU - Buonanno, Giorgio
AU - Hopke, Philip K
AU - Cassee, Flemming
AU - Crape, Byron
N1 - Funding Information:
This study's authors are members of The Chemical and Aerosol Research Team (CART) and the Environment and Resource Efficiency Cluster (EREC). They would like to acknowledge CART and EREC for providing their support to conduct this research. This study's authors truly appreciate the funding provided by Nazarbayev University through the Collaborative Research Grant (grant number: 091019CRP2104) that made this research study possible.
Funding Information:
This study's authors are members of The Chemical and Aerosol Research Team (CART) and the Environment and Resource Efficiency Cluster (EREC). They would like to acknowledge CART and EREC for providing their support to conduct this research. This study's authors truly appreciate the funding provided by Nazarbayev University through the Collaborative Research Grant (grant number: 091019CRP2104) that made this research study possible.
Publisher Copyright:
© 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
PY - 2022/2
Y1 - 2022/2
N2 - Our knowledge of the effects of exposure to indoor ultrafine particles (sub-100 nm, #/cm3) on human brain activity is very limited. The effects of cooking ultrafine particles (UFP) on healthy adults were assessed using an electroencephalograph (EEGs) for brain response. Peak ultrafine particle concentrations were approximately 3 × 105 particle/cm3, and the average level was 1.64 × 105 particle/cm3. The average particle number emission rate (S) and the average number decay rate (a+k) for chicken frying in brain experiments were calculated to be 2.82 × 1012 (SD = 1.83 × 1012, R2 = 0.91, p = 0.0013) particles/min, 0.47 (SD = 0.30, R2 = 0.90, p < 0.0001) min−1, respectively. EEGs were recorded before and during cooking (14 min) and 30 min after the cooking sessions. The brain fast-wave band (beta) decreased during exposure, similar to people with neurodegenerative diseases. It subsequently increased to its pre-exposure condition for 70% of the study participants after 30 min. The brain slow-wave band to fast-wave band ratio (theta/beta ratio) increased during and after exposure, similar to observed behavior in early-stage Alzheimer's disease (AD) patients. The brain then tended to return to its normal condition within 30 min following the exposure. This study suggests that chronically exposed people to high concentrations of cooking aerosol might progress toward AD.
AB - Our knowledge of the effects of exposure to indoor ultrafine particles (sub-100 nm, #/cm3) on human brain activity is very limited. The effects of cooking ultrafine particles (UFP) on healthy adults were assessed using an electroencephalograph (EEGs) for brain response. Peak ultrafine particle concentrations were approximately 3 × 105 particle/cm3, and the average level was 1.64 × 105 particle/cm3. The average particle number emission rate (S) and the average number decay rate (a+k) for chicken frying in brain experiments were calculated to be 2.82 × 1012 (SD = 1.83 × 1012, R2 = 0.91, p = 0.0013) particles/min, 0.47 (SD = 0.30, R2 = 0.90, p < 0.0001) min−1, respectively. EEGs were recorded before and during cooking (14 min) and 30 min after the cooking sessions. The brain fast-wave band (beta) decreased during exposure, similar to people with neurodegenerative diseases. It subsequently increased to its pre-exposure condition for 70% of the study participants after 30 min. The brain slow-wave band to fast-wave band ratio (theta/beta ratio) increased during and after exposure, similar to observed behavior in early-stage Alzheimer's disease (AD) patients. The brain then tended to return to its normal condition within 30 min following the exposure. This study suggests that chronically exposed people to high concentrations of cooking aerosol might progress toward AD.
KW - EEG
KW - frying aerosol
KW - neurodegenerative disease
KW - ultrafine particles
UR - http://www.scopus.com/inward/record.url?scp=85122742196&partnerID=8YFLogxK
U2 - 10.1111/ina.12983
DO - 10.1111/ina.12983
M3 - Article
C2 - 35037300
SN - 0905-6947
VL - 32
SP - 1
EP - 14
JO - Indoor Air
JF - Indoor Air
IS - 2
M1 - e12983
ER -