How the COVID-19 pandemic highlights the necessity of animal research

Lisa Genzel; Roger Adan; Anton Berns; Jeroen van den Beucken; Arjan Blokland; Erik H W G M Boddeke; Willy M Bogers; Ronald Bontrop; R Bulthuis; Teun Bousema; Hans Clevers; Tineke C J J Coenen; Anne-Marie van Dam; Peter M T Deen; K W van Dijk; Bart J L Eggen; Ype Elgersma; Izel Erdogan; Bernard Englitz; J Martje Fentener van Vlissingen; Susanne la Fleur; Ron Fouchier; Carlos P Fitzsimons; Wilbert Frieling; Bart Haagmans; Balthasar A Heesters; Marloes Henckens; Sander Herfst; Elly Hol; Daniel van den Hove; Marien I de Jonge; Jos Jonkers; Leo A B Joosten; Andries Kalsbeek; Maarten Kamermans; Harm H Kampinga; Martien J Kas; J Keijer; Sander Kersten; Amanda J Kiliaan; Taco W A Kooij; Sander Kooijman; Werner J H Koopman; Aniko Korosi; Harm J Krugers; Thijs Kuiken; Steven A Kushner; Jan A M Langermans; Heidi Lesscher; Paul J Lucassen; Esther Lutgens; Mihai G Netea; Lucas P J J Noldus; Jos W M van der Meer; Frank J Meye; Joram D Mul; Kees van Oers; Jocelien D A Olivier; R Jeroen Pasterkamp; Ingrid H C H M Philippens; Jos Prickaerts; Bart J A Pullox; Patrick C N Rensen; Jacco van Rheenen; Ronald P van Rij; Laila Ritsma; Barry H G Rockx; Benno Roozendaal; Evert M van Schothorst; K Stittelaar; Norbert Stockhofe; Dick F Swaab; Rik L de Swart; Louk J M J Vanderschuren; Taco de Vries; Femke de Vrij; Richard van Wezel; Corette J Wierenga; Maximilian Wiesmann; Ingo Willuhn; Chris I de Zeeuw; Judith R Homberg

doi:10.1016/j.cub.2020.08.030

How the COVID-19 pandemic highlights the necessity of animal research

Lisa Genzel
, Roger Adan
, Anton Berns
, Jeroen van den Beucken
, Arjan Blokland
, Erik H W G M Boddeke
, Willy M Bogers
, Ronald Bontrop
, R Bulthuis
, Teun Bousema
, Hans Clevers
, Tineke C J J Coenen
, Anne-Marie van Dam
, Peter M T Deen
, K W van Dijk
, Bart J L Eggen
, Ype Elgersma
, Izel Erdogan
, Bernard Englitz
, J Martje Fentener van Vlissingen

Susanne la Fleur, Ron Fouchier, Carlos P Fitzsimons, Wilbert Frieling, Bart Haagmans, Balthasar A Heesters, Marloes Henckens, Sander Herfst, Elly Hol, Daniel van den Hove, Marien I de Jonge, Jos Jonkers, Leo A B Joosten, Andries Kalsbeek, Maarten Kamermans, Harm H Kampinga, Martien J Kas, J Keijer, Sander Kersten, Amanda J Kiliaan, Taco W A Kooij, Sander Kooijman, Werner J H Koopman, Aniko Korosi, Harm J Krugers, Thijs Kuiken, Steven A Kushner, Jan A M Langermans, Heidi Lesscher, Paul J Lucassen, Esther Lutgens, Mihai G Netea, Lucas P J J Noldus, Jos W M van der Meer, Frank J Meye, Joram D Mul, Kees van Oers, Jocelien D A Olivier, R Jeroen Pasterkamp, Ingrid H C H M Philippens, Jos Prickaerts, Bart J A Pullox, Patrick C N Rensen, Jacco van Rheenen, Ronald P van Rij, Laila Ritsma, Barry H G Rockx, Benno Roozendaal, Evert M van Schothorst, K Stittelaar, Norbert Stockhofe, Dick F Swaab, Rik L de Swart, Louk J M J Vanderschuren, Taco de Vries, Femke de Vrij, Richard van Wezel, Corette J Wierenga, Maximilian Wiesmann, Ingo Willuhn, Chris I de Zeeuw, Judith R Homberg

Radboud University, 6525 XZ Nijmegen, The Netherlands. Electronic address: [email protected].
University Medical Center Utrecht
Netherlands Cancer Institute
Radboud University Medical Center
Maastricht University, 6211 LK Maastricht, The Netherlands.
University of Groningen, 9712 CP Groningen, The Netherlands; University of Groningen, University Medical Center, 9713 GZ Groningen, The Netherlands.
Biomedical Primate Research Center, 2288 GJ Rijswijk, The Netherlands.
Metris BV, 2132 NG Hoofddorp, The Netherlands.
Institute of Psychology, Leiden University, Wassenaarseweg 52, 2333 AK, Leiden, The Netherlands; Department of Psychiatry, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.
Amsterdam University Medical Center
Radboud University Nijmegen
Erasmus University Medical Center Rotterdam
Amsterdam University Medical Centers, 1105 AZ Amsterdam, The Netherlands; Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, 1105 BA Amsterdam, The Netherlands.
Plant Physiology, Swammerdam Institute for Life Sciences, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands.
Charles River, 5231 DD Den Bosch, The Netherlands.
Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands; Oncode Institute, 3521 AL Utrecht, The Netherlands.
Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, 1105 BA Amsterdam, The Netherlands.
Department of Cell Biology, University Medical Center Groningen, University of Groningen, A. Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
University Medical Center Groningen
Wageningen University & Research
Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands; Life and Medical Sciences Institute, University of Bonn, 53115 Bonn, Germany.
Wageningen University, 6708 PB Wageningen, The Netherlands; Netherlands Institute of Ecology, Wageningen University, 6708 PB Wageningen, The Netherlands.
Viroclinics Xplore, 5374 RE Schaijk, The Netherlands.
Wageningen University, 6708 PB Wageningen, The Netherlands; Wageningen Bioveterinary Research, 8221 RA Lelystad, The Netherlands.
Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands; Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, 1105 BA Amsterdam, The Netherlands.
Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands. Electronic address: [email protected].

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Recently, a petition was offered to the European Commission calling for an immediate ban on animal testing. Although a Europe-wide moratorium on the use of animals in science is not yet possible, there has been a push by the non-scientific community and politicians for a rapid transition to animal-free innovations. Although there are benefits for both animal welfare and researchers, advances on alternative methods have not progressed enough to be able to replace animal research in the foreseeable future. This trend has led first and foremost to a substantial increase in the administrative burden and hurdles required to make timely advances in research and treatments for human and animal diseases. The current COVID-19 pandemic clearly highlights how much we actually rely on animal research. COVID-19 affects several organs and systems, and the various animal-free alternatives currently available do not come close to this complexity. In this Essay, we therefore argue that the use of animals is essential for the advancement of human and veterinary health.

Original language	English
Pages (from-to)	R1014-R1018
Journal	Current Biology
Volume	30
Issue number	18
DOIs	https://doi.org/10.1016/j.cub.2020.08.030
Publication status	Published - 21 Sept 2020

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1016/j.cub.2020.08.030

1-s2.0-S0960982220311842-mainFinal published version, 201 KB

Cite this

Genzel, L., Adan, R., Berns, A., van den Beucken, J., Blokland, A., Boddeke, E. H. W. G. M., Bogers, W. M., Bontrop, R., Bulthuis, R., Bousema, T., Clevers, H., Coenen, T. C. J. J., Dam, A.-M. V., Deen, P. M. T., van Dijk, K. W., Eggen, B. J. L., Elgersma, Y., Erdogan, I., Englitz, B., ... Homberg, J. R. (2020). How the COVID-19 pandemic highlights the necessity of animal research. Current Biology, 30(18), R1014-R1018. https://doi.org/10.1016/j.cub.2020.08.030

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title = "How the COVID-19 pandemic highlights the necessity of animal research",

abstract = "Recently, a petition was offered to the European Commission calling for an immediate ban on animal testing. Although a Europe-wide moratorium on the use of animals in science is not yet possible, there has been a push by the non-scientific community and politicians for a rapid transition to animal-free innovations. Although there are benefits for both animal welfare and researchers, advances on alternative methods have not progressed enough to be able to replace animal research in the foreseeable future. This trend has led first and foremost to a substantial increase in the administrative burden and hurdles required to make timely advances in research and treatments for human and animal diseases. The current COVID-19 pandemic clearly highlights how much we actually rely on animal research. COVID-19 affects several organs and systems, and the various animal-free alternatives currently available do not come close to this complexity. In this Essay, we therefore argue that the use of animals is essential for the advancement of human and veterinary health.",

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TY - JOUR

T1 - How the COVID-19 pandemic highlights the necessity of animal research

AU - Genzel, Lisa

AU - Adan, Roger

AU - Berns, Anton

AU - van den Beucken, Jeroen

AU - Blokland, Arjan

AU - Boddeke, Erik H W G M

AU - Bogers, Willy M

AU - Bontrop, Ronald

AU - Bulthuis, R

AU - Bousema, Teun

AU - Clevers, Hans

AU - Coenen, Tineke C J J

AU - Dam, Anne-Marie van

AU - Deen, Peter M T

AU - van Dijk, K W

AU - Eggen, Bart J L

AU - Elgersma, Ype

AU - Erdogan, Izel

AU - Englitz, Bernard

AU - Fentener van Vlissingen, J Martje

AU - la Fleur, Susanne

AU - Fouchier, Ron

AU - Fitzsimons, Carlos P

AU - Frieling, Wilbert

AU - Haagmans, Bart

AU - Heesters, Balthasar A

AU - Henckens, Marloes

AU - Herfst, Sander

AU - Hol, Elly

AU - van den Hove, Daniel

AU - de Jonge, Marien I

AU - Jonkers, Jos

AU - Joosten, Leo A B

AU - Kalsbeek, Andries

AU - Kamermans, Maarten

AU - Kampinga, Harm H

AU - Kas, Martien J

AU - Keijer, J

AU - Kersten, Sander

AU - Kiliaan, Amanda J

AU - Kooij, Taco W A

AU - Kooijman, Sander

AU - Koopman, Werner J H

AU - Korosi, Aniko

AU - Krugers, Harm J

AU - Kuiken, Thijs

AU - Kushner, Steven A

AU - Langermans, Jan A M

AU - Lesscher, Heidi

AU - Lucassen, Paul J

AU - Lutgens, Esther

AU - Netea, Mihai G

AU - Noldus, Lucas P J J

AU - van der Meer, Jos W M

AU - Meye, Frank J

AU - Mul, Joram D

AU - van Oers, Kees

AU - Olivier, Jocelien D A

AU - Pasterkamp, R Jeroen

AU - Philippens, Ingrid H C H M

AU - Prickaerts, Jos

AU - Pullox, Bart J A

AU - Rensen, Patrick C N

AU - van Rheenen, Jacco

AU - van Rij, Ronald P

AU - Ritsma, Laila

AU - Rockx, Barry H G

AU - Roozendaal, Benno

AU - van Schothorst, Evert M

AU - Stittelaar, K

AU - Stockhofe, Norbert

AU - Swaab, Dick F

AU - de Swart, Rik L

AU - Vanderschuren, Louk J M J

AU - de Vries, Taco

AU - de Vrij, Femke

AU - van Wezel, Richard

AU - Wierenga, Corette J

AU - Wiesmann, Maximilian

AU - Willuhn, Ingo

AU - de Zeeuw, Chris I

AU - Homberg, Judith R

PY - 2020/9/21

Y1 - 2020/9/21

N2 - Recently, a petition was offered to the European Commission calling for an immediate ban on animal testing. Although a Europe-wide moratorium on the use of animals in science is not yet possible, there has been a push by the non-scientific community and politicians for a rapid transition to animal-free innovations. Although there are benefits for both animal welfare and researchers, advances on alternative methods have not progressed enough to be able to replace animal research in the foreseeable future. This trend has led first and foremost to a substantial increase in the administrative burden and hurdles required to make timely advances in research and treatments for human and animal diseases. The current COVID-19 pandemic clearly highlights how much we actually rely on animal research. COVID-19 affects several organs and systems, and the various animal-free alternatives currently available do not come close to this complexity. In this Essay, we therefore argue that the use of animals is essential for the advancement of human and veterinary health.

AB - Recently, a petition was offered to the European Commission calling for an immediate ban on animal testing. Although a Europe-wide moratorium on the use of animals in science is not yet possible, there has been a push by the non-scientific community and politicians for a rapid transition to animal-free innovations. Although there are benefits for both animal welfare and researchers, advances on alternative methods have not progressed enough to be able to replace animal research in the foreseeable future. This trend has led first and foremost to a substantial increase in the administrative burden and hurdles required to make timely advances in research and treatments for human and animal diseases. The current COVID-19 pandemic clearly highlights how much we actually rely on animal research. COVID-19 affects several organs and systems, and the various animal-free alternatives currently available do not come close to this complexity. In this Essay, we therefore argue that the use of animals is essential for the advancement of human and veterinary health.

U2 - 10.1016/j.cub.2020.08.030

DO - 10.1016/j.cub.2020.08.030

M3 - Article

C2 - 32961149

SN - 0960-9822

VL - 30

SP - R1014-R1018

JO - Current Biology

JF - Current Biology

IS - 18

ER -

How the COVID-19 pandemic highlights the necessity of animal research

Abstract

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