Healthcare professional surveys to investigate the implementation of the isotretinoin Pregnancy Prevention Programme: a descriptive study

Ineke Crijns; Aukje Mantel-Teeuwisse; Rudi Bloemberg; Eldridge Pinas; Sabine Straus; Lolkje de Jong-van den Berg

doi:10.1517/14740338.2013.745850

Healthcare professional surveys to investigate the implementation of the isotretinoin Pregnancy Prevention Programme: a descriptive study

Ineke Crijns, Aukje Mantel-Teeuwisse, Rudi Bloemberg, Eldridge Pinas, Sabine Straus, Lolkje de Jong-van den Berg

Pharmacoepidemiology and Clinical Pharmacology

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

OBJECTIVE: Three online surveys explored compliance with the PPP by pharmacists and dermatologists, in the Netherlands. In 2007 and 2011, two pharmacist surveys were conducted to assess improvement over time.

METHODS: In 2007, survey was sent to members of the Utrecht Pharmacy Panel for Education & Research (UPPER) network (n = 1000) and in 2011, to the research group of the Dutch Association of Pharmacists (KNMP) (n = 556). In 2010, a survey was sent to 564 dermatologists of the Dutch Association of Dermatology and Venereology (NVDV).

RESULTS: Both pharmacists' questionnaires had response rates of 20% and the dermatologist questionnaire of 28%. Pharmacists' checks on 30-day dispensing remained 82%, but a check whether the prescription is out-of-date decreased (61 to 53%). Pharmacists asked the patient for a negative pregnancy test in 15%, but use of contraception was checked by 44 - 49%. One hundred and five dermatologists (64%) always prescribe contraception; 35 (22%) occasionally. Ninety-three percent of the dermatologists were of the opinion that they performed the PPP. Analysis of different elements of the PPP showed that 41 (25%) were compliant.

CONCLUSIONS: The observed non-adherence to the isotretinoin PPP calls for careful evaluation of risk minimisation plans and participation of all stakeholders in the development of these plans.

Original language	English
Pages (from-to)	29-38
Number of pages	10
Journal	Expert Opinion on Drug Safety
Volume	12
Issue number	1
DOIs	https://doi.org/10.1517/14740338.2013.745850
Publication status	Published - Jan 2013

Keywords

Abnormalities, Drug-Induced
Attitude of Health Personnel
Awareness
Community Pharmacy Services
Contraception
Dermatologic Agents
Dermatology
Drug Prescriptions
Female
Guideline Adherence
Health Care Surveys
Health Knowledge, Attitudes, Practice
Health Plan Implementation
Humans
Isotretinoin
Netherlands
Patient Education as Topic
Practice Guidelines as Topic
Practice Patterns, Physicians'
Pregnancy
Pregnancy Tests
Program Evaluation
Risk Assessment
Risk Factors
Surveys and Questionnaires

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10.1517/14740338.2013.745850

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title = "Healthcare professional surveys to investigate the implementation of the isotretinoin Pregnancy Prevention Programme: a descriptive study",

abstract = "OBJECTIVE: Three online surveys explored compliance with the PPP by pharmacists and dermatologists, in the Netherlands. In 2007 and 2011, two pharmacist surveys were conducted to assess improvement over time.METHODS: In 2007, survey was sent to members of the Utrecht Pharmacy Panel for Education & Research (UPPER) network (n = 1000) and in 2011, to the research group of the Dutch Association of Pharmacists (KNMP) (n = 556). In 2010, a survey was sent to 564 dermatologists of the Dutch Association of Dermatology and Venereology (NVDV).RESULTS: Both pharmacists' questionnaires had response rates of 20% and the dermatologist questionnaire of 28%. Pharmacists' checks on 30-day dispensing remained 82%, but a check whether the prescription is out-of-date decreased (61 to 53%). Pharmacists asked the patient for a negative pregnancy test in 15%, but use of contraception was checked by 44 - 49%. One hundred and five dermatologists (64%) always prescribe contraception; 35 (22%) occasionally. Ninety-three percent of the dermatologists were of the opinion that they performed the PPP. Analysis of different elements of the PPP showed that 41 (25%) were compliant.CONCLUSIONS: The observed non-adherence to the isotretinoin PPP calls for careful evaluation of risk minimisation plans and participation of all stakeholders in the development of these plans.",

keywords = "Abnormalities, Drug-Induced, Attitude of Health Personnel, Awareness, Community Pharmacy Services, Contraception, Dermatologic Agents, Dermatology, Drug Prescriptions, Female, Guideline Adherence, Health Care Surveys, Health Knowledge, Attitudes, Practice, Health Plan Implementation, Humans, Isotretinoin, Netherlands, Patient Education as Topic, Practice Guidelines as Topic, Practice Patterns, Physicians', Pregnancy, Pregnancy Tests, Program Evaluation, Risk Assessment, Risk Factors, Surveys and Questionnaires",

author = "Ineke Crijns and Aukje Mantel-Teeuwisse and Rudi Bloemberg and Eldridge Pinas and Sabine Straus and {de Jong-van den Berg}, Lolkje",

year = "2013",

month = jan,

doi = "10.1517/14740338.2013.745850",

language = "English",

volume = "12",

pages = "29--38",

journal = "Expert Opinion on Drug Safety",

issn = "1474-0338",

publisher = "Taylor and Francis Ltd.",

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}

TY - JOUR

T1 - Healthcare professional surveys to investigate the implementation of the isotretinoin Pregnancy Prevention Programme

T2 - a descriptive study

AU - Crijns, Ineke

AU - Mantel-Teeuwisse, Aukje

AU - Bloemberg, Rudi

AU - Pinas, Eldridge

AU - Straus, Sabine

AU - de Jong-van den Berg, Lolkje

PY - 2013/1

Y1 - 2013/1

N2 - OBJECTIVE: Three online surveys explored compliance with the PPP by pharmacists and dermatologists, in the Netherlands. In 2007 and 2011, two pharmacist surveys were conducted to assess improvement over time.METHODS: In 2007, survey was sent to members of the Utrecht Pharmacy Panel for Education & Research (UPPER) network (n = 1000) and in 2011, to the research group of the Dutch Association of Pharmacists (KNMP) (n = 556). In 2010, a survey was sent to 564 dermatologists of the Dutch Association of Dermatology and Venereology (NVDV).RESULTS: Both pharmacists' questionnaires had response rates of 20% and the dermatologist questionnaire of 28%. Pharmacists' checks on 30-day dispensing remained 82%, but a check whether the prescription is out-of-date decreased (61 to 53%). Pharmacists asked the patient for a negative pregnancy test in 15%, but use of contraception was checked by 44 - 49%. One hundred and five dermatologists (64%) always prescribe contraception; 35 (22%) occasionally. Ninety-three percent of the dermatologists were of the opinion that they performed the PPP. Analysis of different elements of the PPP showed that 41 (25%) were compliant.CONCLUSIONS: The observed non-adherence to the isotretinoin PPP calls for careful evaluation of risk minimisation plans and participation of all stakeholders in the development of these plans.

AB - OBJECTIVE: Three online surveys explored compliance with the PPP by pharmacists and dermatologists, in the Netherlands. In 2007 and 2011, two pharmacist surveys were conducted to assess improvement over time.METHODS: In 2007, survey was sent to members of the Utrecht Pharmacy Panel for Education & Research (UPPER) network (n = 1000) and in 2011, to the research group of the Dutch Association of Pharmacists (KNMP) (n = 556). In 2010, a survey was sent to 564 dermatologists of the Dutch Association of Dermatology and Venereology (NVDV).RESULTS: Both pharmacists' questionnaires had response rates of 20% and the dermatologist questionnaire of 28%. Pharmacists' checks on 30-day dispensing remained 82%, but a check whether the prescription is out-of-date decreased (61 to 53%). Pharmacists asked the patient for a negative pregnancy test in 15%, but use of contraception was checked by 44 - 49%. One hundred and five dermatologists (64%) always prescribe contraception; 35 (22%) occasionally. Ninety-three percent of the dermatologists were of the opinion that they performed the PPP. Analysis of different elements of the PPP showed that 41 (25%) were compliant.CONCLUSIONS: The observed non-adherence to the isotretinoin PPP calls for careful evaluation of risk minimisation plans and participation of all stakeholders in the development of these plans.

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KW - Attitude of Health Personnel

KW - Awareness

KW - Community Pharmacy Services

KW - Contraception

KW - Dermatologic Agents

KW - Dermatology

KW - Drug Prescriptions

KW - Female

KW - Guideline Adherence

KW - Health Care Surveys

KW - Health Knowledge, Attitudes, Practice

KW - Health Plan Implementation

KW - Humans

KW - Isotretinoin

KW - Netherlands

KW - Patient Education as Topic

KW - Practice Guidelines as Topic

KW - Practice Patterns, Physicians'

KW - Pregnancy

KW - Pregnancy Tests

KW - Program Evaluation

KW - Risk Assessment

KW - Risk Factors

KW - Surveys and Questionnaires

U2 - 10.1517/14740338.2013.745850

DO - 10.1517/14740338.2013.745850

M3 - Article

C2 - 23163396

SN - 1474-0338

VL - 12

SP - 29

EP - 38

JO - Expert Opinion on Drug Safety

JF - Expert Opinion on Drug Safety

IS - 1

ER -

Healthcare professional surveys to investigate the implementation of the isotretinoin Pregnancy Prevention Programme: a descriptive study

Abstract

Keywords

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