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Guanidinium Iminosugars as Glycosidase Inhibitors
A. Sevsek
Chemical Biology and Drug Discovery
Chemical Biology and Drug Discovery
Research output
:
Thesis
›
Doctoral thesis 1 (Research UU / Graduation UU)
Overview
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Dive into the research topics of 'Guanidinium Iminosugars as Glycosidase Inhibitors'. Together they form a unique fingerprint.
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Keyphrases
Misfolding
100%
Iminosugars
100%
Glycosidase Inhibitors
100%
Guanidinium
100%
Glucosylceramide
75%
Lysosome
75%
Glucocerebrosidase
75%
Gaucher Disease
75%
PH Dependence
50%
Biological Processes
50%
Therapeutic Approaches
50%
Lysosomal Storage Disease
50%
Pharmacological Chaperone
50%
Active Sites
25%
Catalytic Activity
25%
Potent Inhibitor
25%
Glycoprotein
25%
Small Molecules
25%
Effective Compounds
25%
Glycosphingolipids
25%
Competitive Inhibitor
25%
Therapeutic Strategies
25%
Glycosylation
25%
Metabolic Pathway
25%
Clinical Symptoms
25%
Lysosomal Enzymes
25%
Hydrolysis
25%
Glycolipids
25%
New Therapeutics
25%
Reducing Activity
25%
Positive Outcomes
25%
Target Enzyme
25%
Drug Design
25%
Endoplasmic Reticulum-associated Degradation
25%
Selective Inhibitor
25%
Glycosides
25%
Catabolic Pathway
25%
Cell Concentration
25%
Neurological Complications
25%
GBA1
25%
Glycan Processing
25%
Pharmacological Chaperone Therapy
25%
Processing Enzymes
25%
Carbohydrate Digestion
25%
Pharmacologically Active Compounds
25%
Cellular Dysfunction
25%
Glucocerebrosidase Gene
25%
Biochemical Reactions
25%
Small Components
25%
Glucocerebrosidase Activity
25%
Pharmacology, Toxicology and Pharmaceutical Science
Iminosugar
100%
Glycosidase Inhibitor
100%
Glucosylceramidase
100%
Guanidine
100%
Glucosylceramide
60%
Pharmacological Chaperone
60%
Gaucher's Disease
60%
Lysosome Storage Disease
40%
Drug Development
20%
Competitive Inhibitor
20%
Lysosome Enzyme
20%
Glycoside
20%
Glycan
20%
Receptor
20%
Glycosphingolipid
20%
Glycoprotein
20%
Prematurity
20%
Glycolipid
20%
Neurological Complication
20%
Storage Disease
20%
Biochemistry, Genetics and Molecular Biology
Enzyme
100%
Glycoside Hydrolase
100%
Iminosugar
100%
Glucocerebrosidase
38%
Glucosylceramidase
38%
Lysosome
23%
Pharmacological Chaperone
23%
Gaucher's Disease
23%
Biological Phenomena and Functions Concerning the Entire Organism
15%
Enzymatic Activity
7%
Glycoprotein
7%
Small Molecule
7%
Metabolic Pathway
7%
Enzymatic Hydrolysis
7%
Polysaccharides
7%
Glycosylation
7%
Active Site
7%
Glycoside Hydrolases
7%
Endoplasmic-Reticulum-Associated Protein Degradation
7%
Lysosomal Storage Disease
7%
DNA Template
7%
Competitive Inhibition
7%
Glycoside
7%
Glycosphingolipid
7%
Glycolipid
7%