Genetic risk scores do not improve asthma prediction in childhood

F Nicole Dijk; Charlotte Folkersma; Olena Gruzieva; Ashish Kumar; Alet H Wijga; Ulrike Gehring; Inger Kull; Dirkje S Postma; Judith M Vonk; Erik Melén; Gerard H Koppelman

doi:10.1016/j.jaci.2019.05.017

Genetic risk scores do not improve asthma prediction in childhood

F Nicole Dijk
, Charlotte Folkersma
, Olena Gruzieva
, Ashish Kumar
, Alet H Wijga
, Ulrike Gehring
, Inger Kull
, Dirkje S Postma
, Judith M Vonk
, Erik Melén
, Gerard H Koppelman^*

^*Corresponding author for this work

Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm, Sweden; Centre for Occupational and Environmental Medicine, Stockholm County Council, 104 22 Stockholm, Sweden.
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Department of Public Health Epidemiology, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland.
National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Sachs' Children and Youth Hospital, Södersjukhuset, Stockholm, Sweden; Department of Clinical Science and Education, Södersjukhuset and Karolinska Institutet, Stockholm, Sweden.
University of Groningen, University Medical Center Groningen, Department of Paediatric Pulmonology and Paediatric Allergology, Beatrix Children's Hospital, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.
University Medical Center Groningen
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Sachs' Children and Youth Hospital, Södersjukhuset, Stockholm, Sweden.
Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address: [email protected].

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

Original language	English
Pages (from-to)	857-860.e7
Journal	Journal of Allergy and Clinical Immunology
Volume	144
Issue number	3
DOIs	https://doi.org/10.1016/j.jaci.2019.05.017
Publication status	Published - Sept 2019
Externally published	Yes

Keywords

Asthma/epidemiology
Child
Child, Preschool
Cohort Studies
Disease Susceptibility
Dyspnea/drug therapy
Female
Humans
Infant
Male
Medical History Taking
Models, Theoretical
Polymorphism, Single Nucleotide
Respiratory Sounds
Risk Factors
Steroids/therapeutic use

Access to Document

10.1016/j.jaci.2019.05.017

Cite this

@article{067e456b24bc499681803fabda2d8f1a,

title = "Genetic risk scores do not improve asthma prediction in childhood",

keywords = "Asthma/epidemiology, Child, Child, Preschool, Cohort Studies, Disease Susceptibility, Dyspnea/drug therapy, Female, Humans, Infant, Male, Medical History Taking, Models, Theoretical, Polymorphism, Single Nucleotide, Respiratory Sounds, Risk Factors, Steroids/therapeutic use",

author = "Dijk, \{F Nicole\} and Charlotte Folkersma and Olena Gruzieva and Ashish Kumar and Wijga, \{Alet H\} and Ulrike Gehring and Inger Kull and Postma, \{Dirkje S\} and Vonk, \{Judith M\} and Erik Mel{\'e}n and Koppelman, \{Gerard H\}",

year = "2019",

month = sep,

doi = "10.1016/j.jaci.2019.05.017",

language = "English",

volume = "144",

pages = "857--860.e7",

journal = "Journal of Allergy and Clinical Immunology",

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TY - JOUR

T1 - Genetic risk scores do not improve asthma prediction in childhood

AU - Dijk, F Nicole

AU - Folkersma, Charlotte

AU - Gruzieva, Olena

AU - Kumar, Ashish

AU - Wijga, Alet H

AU - Gehring, Ulrike

AU - Kull, Inger

AU - Postma, Dirkje S

AU - Vonk, Judith M

AU - Melén, Erik

AU - Koppelman, Gerard H

PY - 2019/9

Y1 - 2019/9

KW - Asthma/epidemiology

KW - Child

KW - Child, Preschool

KW - Cohort Studies

KW - Disease Susceptibility

KW - Dyspnea/drug therapy

KW - Female

KW - Humans

KW - Infant

KW - Male

KW - Medical History Taking

KW - Models, Theoretical

KW - Polymorphism, Single Nucleotide

KW - Respiratory Sounds

KW - Risk Factors

KW - Steroids/therapeutic use

U2 - 10.1016/j.jaci.2019.05.017

DO - 10.1016/j.jaci.2019.05.017

M3 - Comment/Letter to the editor

C2 - 31145937

SN - 0091-6749

VL - 144

SP - 857-860.e7

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

IS - 3

ER -