Generating evidence for precision medicine: considerations made by the Ubiquitous Pharmacogenomics Consortium when designing and operationalizing the PREPARE study

Cathelijne H van der Wouden, Stefan Böhringer, Erika Cecchin, Ka-Chun Cheung, Cristina Lucía Dávila-Fajardo, Vera H M Deneer, Vita Dolžan, Magnus Ingelman-Sundberg, Siv Jönsson, Mats O Karlsson, Marjolein Kriek, Christina Mitropoulou, George P Patrinos, Munir Pirmohamed, Emmanuelle Rial-Sebbag, Matthias Samwald, Matthias Schwab, Daniela Steinberger, Julia Stingl, Gere Sunder-PlassmannGiuseppe Toffoli, Richard M Turner, Mandy H van Rhenen, Erik van Zwet, Jesse J Swen, Henk-Jan Guchelaar

Afd Pharmacoepi & Clinical Pharmacology
Pharmacoepidemiology and Clinical Pharmacology
Centre for Clinical Therapeutics

Leiden University Medical Center, Leiden Network for Personalised Therapeutics.
Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.
Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany.
Medicine Information Centre, Royal Dutch Pharmacists Association (KNMP), The Hague, The Netherlands.
Department of Clinical Pharmacy, San Cecilio University Hospital, Instituto de investigación biosanitaria de Granada, ibs.Granada, Granada, Spain.
Pharmacogenetics Laboratory, Faculty of Medicine, Institute of Biochemistry, University of Ljubljana, Slovenia.
Department of Physiology and Pharmacology, Section of Pharmacogenetics, Karolinska Institutet, Stockholm.
Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.
Utrecht University
The Golden Helix Foundation, London, UK.
Department of Pharmacy, University of Patras, School of Health Sciences, University Campus, Rion, Patras, Greece.
Department of Molecular and Clinical Pharmacology, University of Liverpool, and Royal Liverpool University Hospital, Liverpool, UK.
UMR 1027 Inserm and Université de Toulouse III Paul Sabatier, Toulouse, France.
Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Austria.
Department of Pharmacy and Biochemistry, University of Tübingen, Tübingen.
Institute of Human Genetics, Justus Liebig University Giessen.
Institute of Clinical Pharmacology, University Hospital of RWTH Aachen, Aachen, Germany.
Department of Internal Medicine III, Division of Nephrology and Dialysis, Medical University of Venna, Vienna, Austria.
Universitair Medisch Centrum

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Generating evidence for precision medicine: considerations made by the Ubiquitous Pharmacogenomics Consortium when designing and operationalizing the PREPARE study

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Medicine and Dentistry

Pharmacology, Toxicology and Pharmaceutical Science