Functional aliphatic polyesters for biomedical and pharmaceutical applications.

S.H. Seyednejad, A.H. Ghassemi, C.F. van Nostrum, T. Vermonden, W.E. Hennink

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Functional aliphatic polyesters are biodegradable polymers with many possibilities to tune physico-chemical characteristics such as hydrophilicity and degradation rate as compared to traditional polyesters (e.g. PLLA, PLGA and PCL), making the materials suitable for drug delivery or as scaffolds for tissue engineering. Lately, a large number of polyesters have been synthesized by homopolymerization of functionalized monomers or co-polymerization with other monomers mainly via ring-opening polymerization (ROP) of cyclic esters. This review presents the recent trends in the synthesis of these materials and their application for protein delivery and tissue engineering.
Original languageUndefined/Unknown
Pages (from-to)168-76
Number of pages9
JournalJournal of Controlled Release
Volume152
Issue number1
Publication statusPublished - 2011

Keywords

  • Farmacie/Biofarmaceutische wetenschappen (FARM)
  • Medical technology
  • Farmacie(FARM)
  • Biomedische technologie en medicijnen
  • Pharmacology

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