Fibromyalgia

Fibromyalgia is characterized by chronic widespread pain and other symptoms, such as fatigue, waking unrefreshed, and cognitive problems. It is regarded as a primary and nociplastic pain condition. Central sensitization is considered the core pathophysiological mechanism in fibromyalgia, but its cause is unclear. Optimal management requires prompt diagnosis and patient education. Initially, nonpharmacological therapies are recommended, especially exercise. Further therapies should be tailored to the individual and may involve psychological therapies, pharmacotherapy, or multimodal rehabilitation.