Exploitation of gene context

Martijn Huynen; Berend Snel; Warren Lathe III; Peer Bork

doi:10.1016/S0959-440X(00)00098-1

Exploitation of gene context

Martijn Huynen, Berend Snel, Warren Lathe III, Peer Bork

Sub Bioinformatics

Research output: Contribution to journal › Book/Film/Article review › Academic

Abstract

Recently, a number of techniques have been proposed that use completely sequenced genomes for the function prediction of individual proteins encoded therein. They use the fusion of genes, their conserved location in operons or merely their co-occurrence in genomes to predict the existence of functional interactions between the proteins they encode. This type of information complements functional features that are predicted by classical homology-based search techniques.

Original language	English
Pages (from-to)	366-370
Number of pages	5
Journal	Current Opinion in Structural Biology
Volume	10
Issue number	3
DOIs	https://doi.org/10.1016/S0959-440X(00)00098-1
Publication status	Published - 1 Jun 2000

Keywords

bacterial DNA
DNA replication
gene fusion
gene sequence
human
nonhuman
operon
priority journal
protein protein interaction
review
sequence homology

Access to Document

10.1016/S0959-440X(00)00098-1

Cite this

@article{b2639a4c571d4b24880b46c2e24c6229,

title = "Exploitation of gene context",

abstract = "Recently, a number of techniques have been proposed that use completely sequenced genomes for the function prediction of individual proteins encoded therein. They use the fusion of genes, their conserved location in operons or merely their co-occurrence in genomes to predict the existence of functional interactions between the proteins they encode. This type of information complements functional features that are predicted by classical homology-based search techniques.",

keywords = "bacterial DNA, DNA replication, gene fusion, gene sequence, human, nonhuman, operon, priority journal, protein protein interaction, review, sequence homology",

author = "Martijn Huynen and Berend Snel and {Lathe III}, Warren and Peer Bork",

year = "2000",

month = jun,

day = "1",

doi = "10.1016/S0959-440X(00)00098-1",

language = "English",

volume = "10",

pages = "366--370",

journal = "Current Opinion in Structural Biology",

issn = "0959-440X",

publisher = "Elsevier Ltd",

number = "3",

}

TY - JOUR

T1 - Exploitation of gene context

AU - Huynen, Martijn

AU - Snel, Berend

AU - Lathe III, Warren

AU - Bork, Peer

PY - 2000/6/1

Y1 - 2000/6/1

N2 - Recently, a number of techniques have been proposed that use completely sequenced genomes for the function prediction of individual proteins encoded therein. They use the fusion of genes, their conserved location in operons or merely their co-occurrence in genomes to predict the existence of functional interactions between the proteins they encode. This type of information complements functional features that are predicted by classical homology-based search techniques.

AB - Recently, a number of techniques have been proposed that use completely sequenced genomes for the function prediction of individual proteins encoded therein. They use the fusion of genes, their conserved location in operons or merely their co-occurrence in genomes to predict the existence of functional interactions between the proteins they encode. This type of information complements functional features that are predicted by classical homology-based search techniques.

KW - bacterial DNA

KW - DNA replication

KW - gene fusion

KW - gene sequence

KW - human

KW - nonhuman

KW - operon

KW - priority journal

KW - protein protein interaction

KW - review

KW - sequence homology

U2 - 10.1016/S0959-440X(00)00098-1

DO - 10.1016/S0959-440X(00)00098-1

M3 - Book/Film/Article review

SN - 0959-440X

VL - 10

SP - 366

EP - 370

JO - Current Opinion in Structural Biology

JF - Current Opinion in Structural Biology

IS - 3

ER -

Exploitation of gene context

Abstract

Keywords

Access to Document

Fingerprint

Cite this