Evidence of hearing loss and unrelated toxoplasmosis in a free‐ranging harbour porpoise (Phocoena phocoena)

Maria Morell*, Lonneke L. Ijsseldijk, Alinda J. Berends, Andrea Gröne, Ursula Siebert, Stephen A. Raverty, Robert E. Shadwick, Marja J.L. Kik

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Evidence of hearing impairment was identified in a harbour porpoise (Phocoena phocoena) on the basis of scanning electron microscopy. In addition, based on histopathology and immuno-histochemistry, there were signs of unrelated cerebral toxoplasmosis. The six‐year old individual live stranded on the Dutch coast at Domburg in 2016 and died a few hours later. The most significant gross lesion was multifocal necrosis and haemorrhage of the cerebrum. Histopathology of the brain revealed extensive necrosis and haemorrhage in the cerebrum with multifocal accumulations of de-generated neutrophils, lymphocytes and macrophages, and perivascular lymphocytic cuffing. The diagnosis of cerebral toxoplasmosis was confirmed by positive staining of protozoa with anti‐Toxo-plasma gondii antibodies. Tachyzoites were not observed histologically in any of the examined tis-sues. Ultrastructural evaluation of the inner ear revealed evidence of scattered loss of outer hair cells in a 290 μm long segment of the apical turn of the cochlea, and in a focal region of ~ 1.5 mm from the apex of the cochlea, which was compatible with noise‐induced hearing loss. This is the first case of concurrent presumptive noise‐induced hearing loss and toxoplasmosis in a free‐ranging harbour porpoise from the North Sea.

Original languageEnglish
Article number3058
Pages (from-to)1-15
JournalAnimals
Volume11
Issue number11
DOIs
Publication statusPublished - 26 Oct 2021

Keywords

  • Encephalitis
  • Hair cell
  • Inner ear
  • Live stranding
  • Noise‐induced hearing loss
  • North Sea
  • Post‐mortem examination
  • Toxoplasma gondii

Fingerprint

Dive into the research topics of 'Evidence of hearing loss and unrelated toxoplasmosis in a free‐ranging harbour porpoise (Phocoena phocoena)'. Together they form a unique fingerprint.

Cite this