Evaluation of Escherichia coli cell response to antibiotic treatment using laser tweezers Raman spectroscopy

T. Moritz, C.R. Polage, D.S. Taylor, D.M. Krol, S.M. Lane, J.W. Chan

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Laser tweezers Raman spectroscopy was used to detect the cellular response of E. coli cells to penicillin G/streptomycin and cefazolin. Time-dependent intensity changes of several Raman peaks at 729, 1245, and 1660 cm-1 enabled untreated cells and cells treated with the different antibiotic drugs to be distinguished
Original languageEnglish
Pages (from-to)4287-4290
Number of pages4
JournalJournal of Clinical Microbiology
Volume48
Publication statusPublished - 2010

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