ESBL-Producing and Macrolide-Resistant Shigella sonnei Infections among Men Who Have Sex with Men, England, 2015

Piers Mook, Jacquelyn McCormick, Manpreet Bains, Lauren A Cowley, Marie A Chattaway, Claire Jenkins, Amy Mikhail, Gwenda Hughes, Richard Elson, Martin Day, Rohini Manuel, Jayshree Dave, Nigel Field, Gauri Godbole, Timothy Dallman, Paul Crook

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

In England in 2015, Shigella sonnei isolates from men who have sex with men produced extended-spectrum β-lactamases and exhibited macrolide resistance. Whole-genome sequencing showed a close relationship among the isolates, which harbored a plasmid that was previously identified in a shigellosis outbreak among this population but has acquired a mobile element.

Original languageEnglish
Pages (from-to)1948-1952
Number of pages5
JournalEmerging Infectious Diseases
Volume22
Issue number11
DOIs
Publication statusPublished - Nov 2016

Keywords

  • Anti-Bacterial Agents/pharmacology
  • Drug Resistance, Bacterial
  • Dysentery, Bacillary/drug therapy
  • England/epidemiology
  • Genome, Bacterial
  • History, 21st Century
  • Homosexuality, Male
  • Humans
  • Macrolides/pharmacology
  • Male
  • Microbial Sensitivity Tests
  • Phylogeny
  • Polymorphism, Single Nucleotide
  • Shigella sonnei/classification
  • Whole Genome Sequencing
  • beta-Lactamases/biosynthesis

Fingerprint

Dive into the research topics of 'ESBL-Producing and Macrolide-Resistant Shigella sonnei Infections among Men Who Have Sex with Men, England, 2015'. Together they form a unique fingerprint.

Cite this