Eosinophilic keratoconjunctivitis in two rabbits

P. Grinninger, R. Sanchez, I.M.G. Kraijer-Huver, W.J.P. Kitslaar, N.J. Schoemaker, G.C.M. Grinwis, M.H. Boeve

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    Abstract

    Vet Ophthalmol. 2012 Jan;15(1):59-65. doi: 10.1111/j.1463-5224.2011.00920.x. Epub 2011 Aug 8. Eosinophilic keratoconjunctivitis in two rabbits. Grinninger P, Sanchez R, Kraijer-Huver IM, Kitslaar WJ, Schoemaker NJ, Grinwis GC, Boevé MH. Source Ophthalmology section, Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, The Netherlands NKR Veterinary Specialists, 36 Warren Road, Blue Bell Hill, Kent ME5 9RD, UK Division of Zoological Medicine, Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, The Netherlands Division of Pathology, Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, The Netherlands. Abstract The purpose of this case report is to describe the clinical course and cytologic findings, treatment, and outcome of eosinophilic keratoconjunctivitis in two rabbits. Ophthalmic examination revealed ocular discharge, dacryocystitis, blepharitis, conjunctivitis, white conjunctival and corneal plaques, corneal vascularization, and stromal infiltration with different degrees of severity in each case. In case 2 there was also ulcerative disease of the cornea. Computerized tomography scan of the head, corneal biopsy for histopathologic examination with additional Luna and Giemsa stain were performed in case 2 and conjunctival as well as corneal specimens were obtained for bacteriologic culture and cytologic examination in case 1. Based on test results, a diagnosis of eosinophilic keratoconjunctivitis was made in case 2 and a tentative diagnosis of eosinophilic keratoconjunctivitis was made in case 1. Response to treatment with a topical steroid and topical cyclosporin was supportive of the diagnosis in both cases and shared many similarities with the response to treatment previously described in cats. Eosinophilic keratitis should be considered as part of a differential diagnosis list in rabbits with a history of keratitis. © 2011 American College of Veterinary Ophthalmologists
    Original languageEnglish
    Pages (from-to)59-65
    Number of pages7
    JournalVeterinary Ophthalmology
    Volume15
    Issue number1
    DOIs
    Publication statusPublished - 2012

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