Ensemble refinement shows conformational flexibility in crystal structures of human complement factor D

Keyphrases

• Ensemble Refinement 100%
• Conformational Flexibility 100%
• Thrombin 100%
• Human Complement 100%
• Complement Factor D 100%
• Active Sites 33%
• Na + 33%
• Protein Dynamics 33%
• Exosite 33%
• D Variant 33%
• Inactive Conformation 33%
• Well-defined 16%
• X-ray Crystal Structure 16%
• Immune Response 16%
• Native State 16%
• Ligand Binding 16%
• NMR Data 16%
• Enhanced Activity 16%
• Substrate Binding 16%
• Inhibitory Loop 16%
• Enzymatic Activity 16%
• Proteinase 16%
• Active Conformation 16%
• Human Factors 16%
• Thrombin-like 16%
• Conformational Dynamics 16%
• Artificial Peptides 16%
• Serine Proteinase 16%
• Allosteric Regulation 16%
• Rigid Conformation 16%

Biochemistry, Genetics and Molecular Biology

• Crystal Structure 100%
• Factor D 100%
• Thrombin 77%
• Conformation 33%
• Active Site 22%
• Exosite 22%
• Dynamics 22%
• Protein Dynamics 22%
• X Ray 11%
• Ligand Binding 11%
• Allosteric Regulation 11%
• Immune Response 11%
• Enzyme Activity 11%
• Serine Protease 11%
• Protease 11%