Abstract
The encounter complex, i.e., the pre-organized assembly consisting of a Lewis acid and a Lewis base, is a fundamental concept in frustrated Lewis pair (FLP) chemistry. However, this donor acceptor complex is challenging to study due to its transient nature. Here, we present a combined theoretical and experimental investigation on the potential isolation of an encounter complex enabled by enhancement of London dispersion forces between a sterically encumbered Lewis acid and base pair. Guided by computational analyses, the FLP originating from the bulky triarylamine N(3,5-tBu2C6H3)3 and the novel triarylborane B(3,5-tBu2C6H3)3 was investigated, leading to the isolation of at 1:1 co-crystal of both FLP components.
| Original language | English |
|---|---|
| Pages (from-to) | 1122-1128 |
| Number of pages | 7 |
| Journal | Synlett |
| Volume | 34 |
| Issue number | 10 |
| Early online date | 11 Oct 2022 |
| DOIs | |
| Publication status | Published - 2023 |
Bibliographical note
Funding Information:This work was supported by Departlllellt oj Vetera"s Affairs Medical CeJJter R esearch FUllds and ill part by Public Health Sewices rescore/, grallt M01-RR00064 frOIll theNalional Cell terJ or Research Resources. LaurwceJ. Meyer lJIas supported by a career develoPIIICllt award frOIll the DepartllleJIt oJ Veterans Affairs Medical Cellter.
Publisher Copyright:
© 2022 Georg Thieme Verlag. All rights reserved.
Keywords
- frustrated Lewis pairs
- encounter complex
- London dispersion forces
- Lewis acid
- Lewis base