Emergence of novel strains of Shigella flexneri associated with sexual transmission in adult men in England, 2019-2020

Timothy J Dallman; Hannah Charles; Mateo Prochazka; Katy Sinka; Gwenda Hughes; Gauri Godbole; Claire Jenkins

doi:10.1099/jmm.0.001437

Emergence of novel strains of Shigella flexneri associated with sexual transmission in adult men in England, 2019-2020

Timothy J Dallman, Hannah Charles, Mateo Prochazka, Katy Sinka, Gwenda Hughes, Gauri Godbole, Claire Jenkins

IRAS OH Epidemiology Microbial Agents

National Infection Service

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

National surveillance of shigellosis in England revealed an increase in sexually transmitted Shigella flexneri in adult males in 2019 that persisted throughout 2020. We observed a resurgence of azithromycin-resistant S. flexneri serotype 3a, and the emergence of two novel multidrug-resistant clades of S. flexneri 2a and S. flexneri 1b.

Original language	English
Article number	001437
Pages (from-to)	1-7
Journal	Journal of Medical Microbiology
Volume	70
Issue number	10
DOIs	https://doi.org/10.1099/jmm.0.001437
Publication status	Published - Oct 2021

Bibliographical note

Funding Information:
This work was supported by National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Blood Borne and Sexually Transmitted Infections at University College London in partnership with Public Health England (PHE), in collaboration with the London School of Hygiene and Tropical Medicine (LSHTM), and by National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Gastrointestinal Infections at University of Liverpool in partnership with PHE, in collaboration with University of East Anglia, University of Oxford and the Quadram Institute (109524).

Publisher Copyright:
© 2021 The Authors.

Keywords

Multidrug resistance
Sexual transmission
Shigellosis
Surveillance

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Cite this

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title = "Emergence of novel strains of Shigella flexneri associated with sexual transmission in adult men in England, 2019-2020",

abstract = "National surveillance of shigellosis in England revealed an increase in sexually transmitted Shigella flexneri in adult males in 2019 that persisted throughout 2020. We observed a resurgence of azithromycin-resistant S. flexneri serotype 3a, and the emergence of two novel multidrug-resistant clades of S. flexneri 2a and S. flexneri 1b.",

keywords = "Multidrug resistance, Sexual transmission, Shigellosis, Surveillance",

author = "Dallman, {Timothy J} and Hannah Charles and Mateo Prochazka and Katy Sinka and Gwenda Hughes and Gauri Godbole and Claire Jenkins",

note = "Funding Information: This work was supported by National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Blood Borne and Sexually Transmitted Infections at University College London in partnership with Public Health England (PHE), in collaboration with the London School of Hygiene and Tropical Medicine (LSHTM), and by National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Gastrointestinal Infections at University of Liverpool in partnership with PHE, in collaboration with University of East Anglia, University of Oxford and the Quadram Institute (109524). Publisher Copyright: {\textcopyright} 2021 The Authors.",

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AU - Prochazka, Mateo

AU - Sinka, Katy

AU - Hughes, Gwenda

AU - Godbole, Gauri

AU - Jenkins, Claire

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AB - National surveillance of shigellosis in England revealed an increase in sexually transmitted Shigella flexneri in adult males in 2019 that persisted throughout 2020. We observed a resurgence of azithromycin-resistant S. flexneri serotype 3a, and the emergence of two novel multidrug-resistant clades of S. flexneri 2a and S. flexneri 1b.

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Emergence of novel strains of Shigella flexneri associated with sexual transmission in adult men in England, 2019-2020

Abstract

Bibliographical note

Keywords

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