Effects of seasonal allergic rhinitis on driving performance, memory functioning, psychomotor performance and quality of life

M.A.J. Mets, E.R. Volkerts, E.A. Dunnebier, L.M. de Senerpont Domis, B. Olivier, J.C. Verster

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Background: Seasonal allergic rhinitis (SAR) has shown to affect quality of life and impair cognitive functioning. Objective: The objective of this study was to compare driving ability, memory, and psychomotor performance during grass pollen season with winter season in untreated patients with SAR. Methods: Patients with SAR were trained and tested during the grass pollen season (summer) and winter. An on-the-road driving test during normal traffic conditions was performed. Primary parameter is the Standard Deviation of Lateral Position (SDLP), i.e. the weaving of the car. In addition, a word learning test and continuous performance test were performed and quality of life was assessed. Patients were included if in winter the Total 5-Symptoms Score (T5SS) was < 3 and in summer the T5SS was > 3. Results: 70 patients were recruited of which 22 started the study. Fifteen patients completed the study of which 11 met the inclusion criteria. These 11 patients had a mean T5SS of 6.8 in summer and 0.6 in winter. Patient reported a significantly reduced overall quality of life during grass pollen season (p<0.0001). No significant effects were found on the driving test, except a significant (but not relevant) decrease in mean speed during the grass pollen season (p<0.035). No significant effects were found on the word learning test and continuous performance test. Conclusion: Our data suggest that moderate SAR symptoms do not impair driving ability, memory functioning and continuous performance. However, given the small sample size future studies should confirm these findings.
Original languageEnglish
Pages (from-to)19-25
Number of pages7
JournalThe Open Allergy Journal
Volume1
DOIs
Publication statusPublished - 2008

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