Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1(-/-)/Mdr1a/1b(-/-) (triple-knockout) and wild-type mice

S. Marchetti; N.A. de Vries; T. Buckle; M.J. Bolijn; M.A.J. van Eijndhoven; J.H. Beijnen; R. Mazzanti; O. van Tellingen; J.H.M. Schellens

Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1(-/-)/Mdr1a/1b(-/-) (triple-knockout) and wild-type mice

S. Marchetti, N.A. de Vries, T. Buckle, M.J. Bolijn, M.A.J. van Eijndhoven, J.H. Beijnen, R. Mazzanti, O. van Tellingen, J.H.M. Schellens

extern

Research output: Contribution to journal › Article › Academic › peer-review

Original language	Undefined/Unknown
Pages (from-to)	2280-2287
Number of pages	8
Journal	Molecular Cancer Therapeutics
Volume	7
Issue number	8
Publication status	Published - 2008

Cite this

Marchetti, S., de Vries, N. A., Buckle, T., Bolijn, M. J., van Eijndhoven, M. A. J., Beijnen, J. H., Mazzanti, R., van Tellingen, O., & Schellens, J. H. M. (2008). Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1(-/-)/Mdr1a/1b(-/-) (triple-knockout) and wild-type mice. Molecular Cancer Therapeutics, 7(8), 2280-2287.

Marchetti, S. ; de Vries, N.A. ; Buckle, T. et al. / Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1(-/-)/Mdr1a/1b(-/-) (triple-knockout) and wild-type mice. In: Molecular Cancer Therapeutics. 2008 ; Vol. 7, No. 8. pp. 2280-2287.

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title = "Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1(-/-)/Mdr1a/1b(-/-) (triple-knockout) and wild-type mice",

author = "S. Marchetti and {de Vries}, N.A. and T. Buckle and M.J. Bolijn and {van Eijndhoven}, M.A.J. and J.H. Beijnen and R. Mazzanti and {van Tellingen}, O. and J.H.M. Schellens",

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year = "2008",

language = "Undefined/Unknown",

volume = "7",

pages = "2280--2287",

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Marchetti, S, de Vries, NA, Buckle, T, Bolijn, MJ, van Eijndhoven, MAJ, Beijnen, JH, Mazzanti, R, van Tellingen, O & Schellens, JHM 2008, 'Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1(-/-)/Mdr1a/1b(-/-) (triple-knockout) and wild-type mice', Molecular Cancer Therapeutics, vol. 7, no. 8, pp. 2280-2287.

Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1(-/-)/Mdr1a/1b(-/-) (triple-knockout) and wild-type mice. / Marchetti, S.; de Vries, N.A.; Buckle, T. et al.
In: Molecular Cancer Therapeutics, Vol. 7, No. 8, 2008, p. 2280-2287.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1(-/-)/Mdr1a/1b(-/-) (triple-knockout) and wild-type mice

AU - Marchetti, S.

AU - de Vries, N.A.

AU - Buckle, T.

AU - Bolijn, M.J.

AU - van Eijndhoven, M.A.J.

AU - Beijnen, J.H.

AU - Mazzanti, R.

AU - van Tellingen, O.

AU - Schellens, J.H.M.

N1 - ISI:000258860000003

PY - 2008

Y1 - 2008

M3 - Article

SN - 1535-7163

VL - 7

SP - 2280

EP - 2287

JO - Molecular Cancer Therapeutics

JF - Molecular Cancer Therapeutics

IS - 8

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Marchetti S, de Vries NA, Buckle T, Bolijn MJ, van Eijndhoven MAJ, Beijnen JH et al. Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1(-/-)/Mdr1a/1b(-/-) (triple-knockout) and wild-type mice. Molecular Cancer Therapeutics. 2008;7(8):2280-2287.