Effect of salmon gonadotropic hormone on sex steroids in male rainbow trout: plasma levels and testicular secretion in vitro.

R.W. Schulz, M. Andriske, P.J. Lembke, V. Blüm

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Male rainbow trout were treated with salmon gonadotropic hormone (GTH) at different stages of the circannual reproductive cycle; spawning fish were also treated with an antiserum against salmon GTH. Injection of GTH led to a several-fold increase of plasma sex steroid levels during spermatogenesis and in the spawning season but was without effect at early stages of testicular development. GTH neutralization during the spawning season was followed by a several-fold decrease of plasma sex steroid levels. During spermatogenesis and in the spawning season, both treatment regimes resulted in an increased sensitivity of testicular explants in response to a subsequent stimulation of steroid secretion in vitro. This up-regulatory response may facilitate and maintain the high sex steroid plasma levels observed during the spawning season. It may also be necessary to allow for concomitant peak values of plasma GTH and sex steroids in the spawning season, a situation difficult to understand within the negative feedback concept. The adaptive capacities of the testicular steroidogenic system indicate that it is not only an effector site for GTH but also an active part of the endocrine system controling reproduction.
Original languageEnglish
Pages (from-to)224-230
Number of pages7
JournalJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology
Volume162
Issue number3
Publication statusPublished - 1 Jan 1992
Externally publishedYes

Keywords

  • gonadotropin
  • sex hormone
  • steroid
  • animal
  • article
  • blood
  • drug antagonism
  • drug effect
  • in vitro study
  • male
  • physiology
  • reproduction
  • salmonine
  • season
  • secretion (process)
  • testis
  • upregulation

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