Abstract
The clinical manifestation of mange in a guinea-pig population in Utrecht is discussed. The etiology and the treatment with two subcutaneous injections of ivermectin 0.2 mg/kg with a ten-day interval, is described. A total of 37 guinea-pigs with symptoms and 36 guinea-pig without signs of mange were treated. On the 21st day all previously infested guinea-pigs were free of symptoms. During this study side-effects occurred in 11 of the 73 animals. The most prominent side-effects were a (sub-)dermal necrosis in the younger animals and an inflammation of the cutis in the older animals. The side-effects were probably caused by propylene glycol which was used as a diluent.
| Translated title of the contribution | A field study of the efficacy of ivermectin in propylene glycol in the treatment of mange in guinea pigs |
|---|---|
| Original language | Dutch |
| Pages (from-to) | 42-6 |
| Number of pages | 5 |
| Journal | Tijdschrift voor Diergeneeskunde |
| Volume | 118 |
| Issue number | 2 |
| Publication status | Published - 15 Jan 1993 |
Keywords
- Animals
- Drug Carriers
- Guinea Pigs
- Ivermectin
- Necrosis
- Propylene Glycols
- Scabies
- Skin