DNA variants in the human RAB3A gene are not associated with autism

P D'Adamo; E Bacchelli; F Blasi; HP Lipp; D Toniolo; E Maestrini; Int Molecular Genetic Study Austis; Chantal Kemner

doi:10.1111/j.1601-183X.2003.00058.x

DNA variants in the human RAB3A gene are not associated with autism

P D'Adamo^*, E Bacchelli, F Blasi, HP Lipp, D Toniolo, E Maestrini, Int Molecular Genetic Study Austis, Chantal Kemner

^*Corresponding author for this work

Leerstoel Kemner

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Mutation screening of the RAB3A gene in 47 individuals with autism provided no evidence that DNA variants in this gene are associated with autism. Since Rab3a constitutive knockout mice react to novel stimuli with hyperactivity, a further search for association of RAB3A DNA variants with other neurobehavioral disorders such as attention deficit/hyperactivity disorder appears justified.

Original language	English
Pages (from-to)	123-124
Number of pages	2
Journal	Genes, Brain, and Behavior
Volume	3
Issue number	2
DOIs	https://doi.org/10.1111/j.1601-183X.2003.00058.x
Publication status	Published - Apr 2004

Keywords

ADHD
autism
human
mouse
mutation
Rab3a
GENOMEWIDE SCREEN
LINKAGE
7Q

Access to Document

10.1111/j.1601-183X.2003.00058.x

Cite this

@article{1aea26b0899a4666a7e0e16978c766e4,

title = "DNA variants in the human RAB3A gene are not associated with autism",

abstract = "Mutation screening of the RAB3A gene in 47 individuals with autism provided no evidence that DNA variants in this gene are associated with autism. Since Rab3a constitutive knockout mice react to novel stimuli with hyperactivity, a further search for association of RAB3A DNA variants with other neurobehavioral disorders such as attention deficit/hyperactivity disorder appears justified.",

keywords = "ADHD, autism, human, mouse, mutation, Rab3a, GENOMEWIDE SCREEN, LINKAGE, 7Q",

author = "P D'Adamo and E Bacchelli and F Blasi and HP Lipp and D Toniolo and E Maestrini and {Int Molecular Genetic Study Austis} and Chantal Kemner",

year = "2004",

month = apr,

doi = "10.1111/j.1601-183X.2003.00058.x",

language = "English",

volume = "3",

pages = "123--124",

journal = "Genes, Brain, and Behavior",

issn = "1601-1848",

publisher = "Wiley-Blackwell",

number = "2",

}

TY - JOUR

T1 - DNA variants in the human RAB3A gene are not associated with autism

AU - D'Adamo, P

AU - Bacchelli, E

AU - Blasi, F

AU - Lipp, HP

AU - Toniolo, D

AU - Maestrini, E

AU - Int Molecular Genetic Study Austis

AU - Kemner, Chantal

PY - 2004/4

Y1 - 2004/4

N2 - Mutation screening of the RAB3A gene in 47 individuals with autism provided no evidence that DNA variants in this gene are associated with autism. Since Rab3a constitutive knockout mice react to novel stimuli with hyperactivity, a further search for association of RAB3A DNA variants with other neurobehavioral disorders such as attention deficit/hyperactivity disorder appears justified.

AB - Mutation screening of the RAB3A gene in 47 individuals with autism provided no evidence that DNA variants in this gene are associated with autism. Since Rab3a constitutive knockout mice react to novel stimuli with hyperactivity, a further search for association of RAB3A DNA variants with other neurobehavioral disorders such as attention deficit/hyperactivity disorder appears justified.

KW - ADHD

KW - autism

KW - human

KW - mouse

KW - mutation

KW - Rab3a

KW - GENOMEWIDE SCREEN

KW - LINKAGE

KW - 7Q

U2 - 10.1111/j.1601-183X.2003.00058.x

DO - 10.1111/j.1601-183X.2003.00058.x

M3 - Article

SN - 1601-1848

VL - 3

SP - 123

EP - 124

JO - Genes, Brain, and Behavior

JF - Genes, Brain, and Behavior

IS - 2

ER -

DNA variants in the human RAB3A gene are not associated with autism

Abstract

Keywords

Access to Document

Fingerprint

Cite this