DNA-AMPLIFICATIE EN DE ANALYSE VAN GENDEFECTEN

J. A. Lenstra

DNA-AMPLIFICATIE EN DE ANALYSE VAN GENDEFECTEN

Translated title of the contribution: DNA amplification and the analysis of gene defects

J. A. Lenstra^*

^*Corresponding author for this work

Faculty of Veterinary Medicine

Utrecht University

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

A survey of the DNA techniques is presented. The development of the polymerase chain reaction (PCR) has made the DNA technology accessible for routine testing. Any DNA fragment from which the sequence is available can be amplified in vitro. This offers wide perspectives for genetic and microbiological diagnosis, histocompatibility tests and the analysis of mutations in tumors. A number of methods to analyse gen defects in amplified DNA is discussed.

Translated title of the contribution	DNA amplification and the analysis of gene defects
Original language	Dutch
Pages (from-to)	276-281
Number of pages	6
Journal	Nederlands tijdschrift voor klinische chemie
Volume	20
Issue number	6
Publication status	Published - 1 Jan 1995

Keywords

clinical chemistry
genetic defects
PCR

Cite this

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abstract = "A survey of the DNA techniques is presented. The development of the polymerase chain reaction (PCR) has made the DNA technology accessible for routine testing. Any DNA fragment from which the sequence is available can be amplified in vitro. This offers wide perspectives for genetic and microbiological diagnosis, histocompatibility tests and the analysis of mutations in tumors. A number of methods to analyse gen defects in amplified DNA is discussed.",

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AB - A survey of the DNA techniques is presented. The development of the polymerase chain reaction (PCR) has made the DNA technology accessible for routine testing. Any DNA fragment from which the sequence is available can be amplified in vitro. This offers wide perspectives for genetic and microbiological diagnosis, histocompatibility tests and the analysis of mutations in tumors. A number of methods to analyse gen defects in amplified DNA is discussed.

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KW - genetic defects

KW - PCR

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SN - 1380-3689

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JF - Nederlands tijdschrift voor klinische chemie

IS - 6

ER -

DNA-AMPLIFICATIE EN DE ANALYSE VAN GENDEFECTEN

Abstract

Keywords

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