TY - JOUR
T1 - Discrepancy in rating health-related quality of life of depression between patient and general population
AU - Gerhards, S.A.H.
AU - Evers, S.M.A.A.
AU - Sabel, P.W.M.
AU - Huibers, M.J.H.
N1 - Funding Information:
Acknowledgments We thank Esther de Graaf, Annie Hendriks and Greet Kellens for their assistance in recruitment and data-collection, and Rosanne Janssen for the development of the infrastructure for online data-collection. This study collected data within the screening for a trial financed by ZonMw (Netherlands Organisation for Health Research and Development; project number 945-04-417), research institute EPP and research institute CAPHRI. Municipalities Eijsden, Meerssen, Sittard-Geleen, Valkenburg and Maastricht sponsored the trial study. The study sponsors had no role in the design of the study; in the collection, analysis, and interpretation of the data; in the writing of the report; and in the decision to submit the article for publication.
PY - 2011
Y1 - 2011
N2 - Objective: To compare the quality of life valuation of a hypothetical depression health state between a general population versus a depressive patient population, and within a patient population. Method: In a self-administered Internet questionnaire, both patient and general population groups filled in the Euroqol 5D (EQ-5D) questionnaire for a hypothetical depression health state describing mild (N = 740), moderate (N = 691), or severe (N = 670) depression and valued it using a rating scale (RS). The 'patient' group consisted of people reporting depressive complaints on the Internet questionnaire, subdivided into three depression severity groups (mild, moderate, severe) based on the Beck Depression Inventory Second Edition (BDI-II) and two groups according to self-perceived duration (≤3 months, ≥4 months) of depressive complaints (SPDD). Results: Significant differences were found between the patient and general population and within the patient population on RS outcomes and on the Euroqol domains usual activities, pain/discomfort, and anxiety/depression. The direction of the differences shows that subgroups with higher severity or longer duration of depressive complaints value depression health states worse compared with subgroups with less severe complaints, a shorter duration, or no depressive complaints. Moreover, the discrepancy in valuation of a health state between different subgroups changes according to the severity of the health state described. Conclusion: There are discrepancies in the valuation of a hypothetical depression health state between a patient and general population, whereby depression leads to a worse valuation. But also within the patient population, the valuation differs according to depression severity and duration. Identification with the hypothetical health state description might explain the varying differences found between subgroups for the different hypothetical health state descriptions.
AB - Objective: To compare the quality of life valuation of a hypothetical depression health state between a general population versus a depressive patient population, and within a patient population. Method: In a self-administered Internet questionnaire, both patient and general population groups filled in the Euroqol 5D (EQ-5D) questionnaire for a hypothetical depression health state describing mild (N = 740), moderate (N = 691), or severe (N = 670) depression and valued it using a rating scale (RS). The 'patient' group consisted of people reporting depressive complaints on the Internet questionnaire, subdivided into three depression severity groups (mild, moderate, severe) based on the Beck Depression Inventory Second Edition (BDI-II) and two groups according to self-perceived duration (≤3 months, ≥4 months) of depressive complaints (SPDD). Results: Significant differences were found between the patient and general population and within the patient population on RS outcomes and on the Euroqol domains usual activities, pain/discomfort, and anxiety/depression. The direction of the differences shows that subgroups with higher severity or longer duration of depressive complaints value depression health states worse compared with subgroups with less severe complaints, a shorter duration, or no depressive complaints. Moreover, the discrepancy in valuation of a health state between different subgroups changes according to the severity of the health state described. Conclusion: There are discrepancies in the valuation of a hypothetical depression health state between a patient and general population, whereby depression leads to a worse valuation. But also within the patient population, the valuation differs according to depression severity and duration. Identification with the hypothetical health state description might explain the varying differences found between subgroups for the different hypothetical health state descriptions.
KW - Depression
KW - EQ-5D
KW - Health-related quality-of-life
KW - Patient preferences
KW - Population preferences
KW - Rating scale
UR - http://www.scopus.com/inward/record.url?scp=79952243670&partnerID=8YFLogxK
U2 - 10.1007/s11136-010-9746-x
DO - 10.1007/s11136-010-9746-x
M3 - Article
C2 - 20882357
AN - SCOPUS:79952243670
SN - 0962-9343
VL - 20
SP - 273
EP - 279
JO - Quality of Life Research
JF - Quality of Life Research
IS - 2
ER -