Abstract
PURPOSE: To determine whether there were discrepancies between with coumarin anticoagulants interacting medications recorded in medical files of anticoagulation clinics (AC-records) and computerized records of community pharmacies (pharmacy records).
METHODS: A descriptive study was conducted at two Dutch anticoagulation clinics (AC's). Records of with coumarin anticoagulants interacting drugs at the AC's were compared with the pharmacy records. A drug registered in the pharmacy records but not in the AC-records, was recorded as a discrepancy, while a drug registered in AC-records as well as in pharmacy records, was recorded as a match.
RESULTS: Of the 117 identified interacting drugs registered in pharmacy records 32 (27%) were not registered in the AC-records. In four out of seven patients of whom the use of a pharmacokinetically interacting drug was not registered in the AC-records, several INR-values exceeded the upper therapeutic range.
CONCLUSION: This study demonstrates that a substantial percentage of drugs of which an interaction with coumarin anticoagulants can be expected, is not registered in the medical files of anticoagulation clinics.
| Original language | English |
|---|---|
| Pages (from-to) | 823-828 |
| Number of pages | 6 |
| Journal | Pharmacoepidemiology and Drug Safety |
| Volume | 15 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - Nov 2006 |
Keywords
- Aged
- Ambulatory Care Facilities
- Anticoagulants
- Community Pharmacy Services
- Drug Interactions
- Drug Monitoring
- Drug Prescriptions
- Drug Therapy, Combination
- Drug Utilization
- Humans
- International Normalized Ratio
- Medical Records
- Medical Records Systems, Computerized
- Middle Aged
- Netherlands
- Patient Education as Topic
- Pharmacoepidemiology
- Prospective Studies
- Quality Assurance, Health Care
- Registries