Discovery of new feline paramyxoviruses in domestic cats with chronic kidney disease

Michael Sieg; Kristin Heenemann; Antje Rückner; Iwan Burgener; Gerhard Oechtering; Thomas W Vahlenkamp

doi:10.1007/s11262-015-1232-7

Discovery of new feline paramyxoviruses in domestic cats with chronic kidney disease

Michael Sieg, Kristin Heenemann, Antje Rückner, Iwan Burgener, Gerhard Oechtering, Thomas W Vahlenkamp

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Paramyxoviruses constitute a large family of enveloped RNA viruses including important pathogens in veterinary and human medicine. Recently, feline paramyxoviruses, genus morbillivirus, were detected in cats from Hong Kong and Japan. Here we describe the discovery of several new feline paramyxoviruses. Infections with these diverse viruses were detected in urine samples from cats suffering from chronic kidney disease (CKD). No viral RNA was found in cats without clinical signs of uropathy highlighting an association between feline paramyxovirus (FPaV) infections and CKD. Phylogenetic analyses of the detected viruses showed that they represent at least two different species, one of them representing the feline morbilliviruses detected previously in Hong Kong and Japan. In addition, a new FPaV was detected sharing only 73 % homology on the nucleotide level of the viral L-gene to currently known paramyxoviral species.

Original language	English
Journal	Virus Genes
DOIs	https://doi.org/10.1007/s11262-015-1232-7
Publication status	Published - 12 Aug 2015

Keywords

Cat
FLUTD
Paramyxoviruses
Urine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/s11262-015-1232-7

discoveryFinal published version, 437 KBLicence: Taverne

Cite this

@article{9d431e80713d4f0d900e3b26758e2368,

title = "Discovery of new feline paramyxoviruses in domestic cats with chronic kidney disease",

abstract = "Paramyxoviruses constitute a large family of enveloped RNA viruses including important pathogens in veterinary and human medicine. Recently, feline paramyxoviruses, genus morbillivirus, were detected in cats from Hong Kong and Japan. Here we describe the discovery of several new feline paramyxoviruses. Infections with these diverse viruses were detected in urine samples from cats suffering from chronic kidney disease (CKD). No viral RNA was found in cats without clinical signs of uropathy highlighting an association between feline paramyxovirus (FPaV) infections and CKD. Phylogenetic analyses of the detected viruses showed that they represent at least two different species, one of them representing the feline morbilliviruses detected previously in Hong Kong and Japan. In addition, a new FPaV was detected sharing only 73 % homology on the nucleotide level of the viral L-gene to currently known paramyxoviral species.",

keywords = "Cat, FLUTD, Paramyxoviruses , Urine ",

author = "Michael Sieg and Kristin Heenemann and Antje R{\"u}ckner and Iwan Burgener and Gerhard Oechtering and Vahlenkamp, {Thomas W}",

year = "2015",

month = aug,

day = "12",

doi = "10.1007/s11262-015-1232-7",

language = "English",

journal = "Virus Genes",

issn = "0920-8569",

publisher = "Springer",

}

TY - JOUR

T1 - Discovery of new feline paramyxoviruses in domestic cats with chronic kidney disease

AU - Sieg, Michael

AU - Heenemann, Kristin

AU - Rückner, Antje

AU - Burgener, Iwan

AU - Oechtering, Gerhard

AU - Vahlenkamp, Thomas W

PY - 2015/8/12

Y1 - 2015/8/12

N2 - Paramyxoviruses constitute a large family of enveloped RNA viruses including important pathogens in veterinary and human medicine. Recently, feline paramyxoviruses, genus morbillivirus, were detected in cats from Hong Kong and Japan. Here we describe the discovery of several new feline paramyxoviruses. Infections with these diverse viruses were detected in urine samples from cats suffering from chronic kidney disease (CKD). No viral RNA was found in cats without clinical signs of uropathy highlighting an association between feline paramyxovirus (FPaV) infections and CKD. Phylogenetic analyses of the detected viruses showed that they represent at least two different species, one of them representing the feline morbilliviruses detected previously in Hong Kong and Japan. In addition, a new FPaV was detected sharing only 73 % homology on the nucleotide level of the viral L-gene to currently known paramyxoviral species.

AB - Paramyxoviruses constitute a large family of enveloped RNA viruses including important pathogens in veterinary and human medicine. Recently, feline paramyxoviruses, genus morbillivirus, were detected in cats from Hong Kong and Japan. Here we describe the discovery of several new feline paramyxoviruses. Infections with these diverse viruses were detected in urine samples from cats suffering from chronic kidney disease (CKD). No viral RNA was found in cats without clinical signs of uropathy highlighting an association between feline paramyxovirus (FPaV) infections and CKD. Phylogenetic analyses of the detected viruses showed that they represent at least two different species, one of them representing the feline morbilliviruses detected previously in Hong Kong and Japan. In addition, a new FPaV was detected sharing only 73 % homology on the nucleotide level of the viral L-gene to currently known paramyxoviral species.

KW - Cat

KW - FLUTD

KW - Paramyxoviruses

KW - Urine

U2 - 10.1007/s11262-015-1232-7

DO - 10.1007/s11262-015-1232-7

M3 - Article

C2 - 26265247

SN - 0920-8569

JO - Virus Genes

JF - Virus Genes

ER -

Discovery of new feline paramyxoviruses in domestic cats with chronic kidney disease

Abstract

Keywords

UN SDGs

Access to Document

Fingerprint

Cite this